Journal of Dali University ›› 2023, Vol. 8 ›› Issue (2): 51-55.

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Study of the Distribution of High-Risk Human Papilloma Virus Subtypes in Liangshan Region Sichuan Province

Chen Huaqiu1 Chen Xingyou2 Wang Guangming3*   

  1. 1. Department of Laboratory Xichang People's Hospital Xichang Sichuan 615000 China 2. Department of Pathology Xichang People's Hospital Xichang Sichuan 615000 China 3. Gene Testing Center The First Affiliated Hospital of Dali University Dali Yunnan 671000 China

  • Received:2022-04-05 Revised:2022-06-14 Online:2023-02-15 Published:2023-03-02

Abstract: Objective To understand the characteristics of high-risk human papillomavirus HR-HPV infection among women in Liangshan Region Sichuan Province and to provide data support for the development and application of HPV vaccine in this area.Methods The PCR fluorescence probe method was used to detect HR-HPV in 7 445 women who visited the physical examination center of Xichang People's Hospital and the outpatient department of obstetrics and gynecology from November 142018 to December 302020 and the detection results were statistically analyzed. ResultsAmong the 7 445 samples 1 027 were HR-HPV positive with a positive rate of 13.79% and all 15 HR-HPV subtypes were detected. Among them 818 cases 79.65% were single infection and 209 cases 20.35% were multiple infection. The top three subtypes of HR-HPV infection were HPV 52 16 and 53. In all age groups the positive rate of subjects aged 61 years was the highest 22.39%), followed by subjects aged 21-30 years 15.86%. Conclusion The distribution of HR-HPV subtype infection in Liangshan Region Sichuan Province has certain regional characteristics and the positive rate is the highest among people over 61 years old. Therefore it is necessary to strengthen the publicity of HR-HPV screening among the suitable age population.

Key words: font-family:Times New Roman, ">high-risk human papilloma virusfont-family:Times New Roman, ">, font-family:Times New Roman, "> PCR fluorescence probe methodfont-family:Times New Roman, ">, font-family:Times New Roman, "> cervical carcinoma

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