大理大学学报 ›› 2020, Vol. 5 ›› Issue (2): 76-79.DOI: 10. 3969 / j. issn. 2096-2266. 2020. 02. 017

• 临床医学 • 上一篇    下一篇

血清降钙素原在滇藏线重症交通创伤患者感染中的作用与应用

李 倩,杨政标,朱麒宇,张胜梅   

  1. (中国人民解放军32268部队检验科,云南大理 671003)
  • 收稿日期:2019-02-07 修回日期:2019-05-05 出版日期:2020-02-15 发布日期:2020-02-15
  • 作者简介:李倩,检验技师,主要从事医学检验研究

The Role and Application of Serum Procalcitonin in Infections of Patients Suffering Severe Traffic#br# Trauma on Yunnan-Tibet Highway

Li Qian, Yang Zhengbiao, Zhu Qiyu, Zhang Shengmei   

  1. (Department of Clinical Laboratory, 32268 Army of Chinese PLA, Dali, Yunnan 671003, China)
  • Received:2019-02-07 Revised:2019-05-05 Online:2020-02-15 Published:2020-02-15

摘要: 目的:探讨血清降钙素原(PCT)在滇藏线重症交通创伤患者感染中的临床作用。方法:选取2015年1月至2017年12月
在滇藏线沿线发生交通事故后被收治到中国人民解放军32268部队(原解放军第60中心医院)的以颅脑外伤、肝脾破裂、胸腹
联合伤或多发伤为主的重症患者1 396例,对其进行PCT及血培养、分泌物培养连续检测的观察,分析PCT在诊断滇藏线重症
交通创伤患者感染中的价值。结果:感染组患者PCT水平显著高于对照组[(5.38±2.71)vs.(0.56±0.42)ng/mL,P<0.01];PCT
在诊断滇藏线重症交通创伤患者感染中ROC曲线下面积为[0.897(0.778~0.981),P<0.01];感染组患者发热24 h时血培养的
阳性率为16.39%,而PCT检测阳性率为80.60%;革兰阴性菌感染的患者PCT水平明显高于革兰阳性菌感染的患者。结论:
PCT可以作为滇藏线重症交通创伤患者感染的诊断指标。

关键词: 降钙素原, 滇藏线, 重症, 交通伤, 感染

Abstract: Objective:Toinvestigatetheclinicaleffectsofserum procalcitonininpatientswhosufferedseveretraffictraumaonYunnan-
Tibet Highway. Methods: From January 2015 to December 2017, 1 396 patients with severe head injuries, liver and spleen ruptures,
thoracoabdominal injuries or multiple injuries who were admitted to 32268 Army of Chinese PLA after traffic accidents on Yunnan-Tibet
Highway were selected and observed for PCT, blood culture and secretion culture. The value of PCT in diagnosing the infections of
patients who suffered severe traffic trauma on Yunnan-Tibet Highway was analyzed. Results: The PCT level of patients in the infected
group was significantly higher than that in the control group[(5.38±2.71)vs.(0.56±0.42)ng/mL, P<0.01]; the area under ROC curve of
PCT in the diagnosis of patients who suffered severe traffic trauma on Yunnan-Tibet Highway was[0.897(0.778-0.981), P < 0.01]; The
positive rate of blood culture was 16.39% and PCT was 80.60% in the infected group after 24 hours of fever. PCT level of patients infected
with gram-negative bacilli was significantly higher than that of patients infected with gram-positive bacilli. Conclusion: PCT can be
used as a diagnostic index for infections of patients who suffered severe traffic trauma on Yunnan-Tibet Highway.

Key words: procalcitonin, Yunnan-Tibet Highway, severe, traffic injuries, infection