J4 ›› 2016, Vol. 1 ›› Issue (8): 1-.DOI: 10. 3969 / j. issn. 2096-2266

• 药学 •    下一篇

云南松松塔提取物对正常小鼠免疫功能的影响

  

  • 发布日期:2016-08-25

The Effect of Pinecone Extract of Pinus Yunnanensis on Immune Function of Normal Mice

  • Published:2016-08-25

摘要:

[摘要]目的:研究云南松松塔提取物对正常小鼠免疫功能的影响。方法:昆明种小鼠灌胃给予高、中、低剂量(400、200、100
mg/kg)的松塔提取物,阳性对照药左旋咪唑(25 mg/kg),连续给药10 d后,处死小鼠,测定小鼠血清中免疫球蛋白IgA、IgM、IgG
和补体C3、C4的含量,测全外周血细胞数,计算脾脏指数和胸腺指数。结果:云南松松塔提取物能增加外周血中的免疫球蛋白
IgA、IgM、补体C4的含量和白细胞数,与正常组相比差异均具有统计学意义(P <0.05)。结论:云南松松塔提取物对正常小鼠的
免疫功能有一定的增强作用。

关键词: 云南松;松塔;正常小鼠;免疫球蛋白;补体;外周血细胞

Abstract:

〔Abstract〕Objective: To study the effect of pinecone extract of Pinus Yunnanensis on immune function of normal mice. Methods:
Kunming mice were administered high, middle and low dose of pinecone extract(400,200,100 mg/kg), 25 mg/kg Levamisole by gavage
and the mice were sacrificed after 10 days. The content of immunoglobulin IgA, IgM, IgG, complement C3 and C4 in mice serum was
measured; the amount of peripheral blood cell, spleen index, and thymus index were measured as well. Results: The pinecone extract
of Pinus Yunnanensis could increase immunoglobulin IgA, IgM, complements C4 and WBC in peripheral blood content. Compared with
normal group, the difference reflects statistical significance(P <0.05). Conclusion: The pinecone extract of Pinus Yunnanensis can
enhance the immune function of normal mice .

Key words: 〔Key words〕Pinus yunnanensis;pinecone;normal mice;immunoglobulin;complement;peripheral blood cell

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