›› 2018, Vol. 3 ›› Issue (6): 69-72.

• 化学 • 上一篇    下一篇

含氟牙膏再矿化根面龋的体外研究

  

  1. (大理大学药学与化学学院,云南大理671000)
  • 收稿日期:2017-05-03 出版日期:2018-06-15 发布日期:2018-06-15
  • 作者简介:崔霞,2014级药学专业本科生.
  • 基金资助:

    大理大学大学生科研基金资助项目(KYSX201673)

Experimental Study on the Effect of Fluoride Toothpaste on Remineralization
of Artificial Root Caries in vitro

  1. (College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China)
  • Received:2017-05-03 Online:2018-06-15 Published:2018-06-15

摘要:

目的:研究含氟牙膏及添加NaF分别为10、20、40 mg/L的不含氟牙膏促进根面龋的再矿化效果。方法:采用离体牛切
牙制备人工离体牙根组织块,开窗,置37 ℃脱矿液中96 h,形成人工根面龋后,随机分组。每组6个样本,依次进行再矿化循
环,每天6次,循环8 d,应用偏光显微镜观察各组样本再矿化循环后的形态学变化。结果:含氟牙膏组可见不同程度的矿物质
沉积,其沉积带宽度排列为:黑人>纳爱斯>高露洁;加NaF的不含氟牙膏组沉积带宽度排列为:40 mg/L>20 mg/L>10 mg/L。结
论:含氟牙膏中黑人牙膏的再矿化效果最好,含NaF 40 mg/L的不含氟牙膏再矿化效果最好。

关键词: 含氟牙膏, 牙根龋, 再矿化, 偏光显微镜

Abstract:

Objective:The paper is to study the remineralized effects on root caries of different kinds of fluoride toothpaste and
fluoride- free toothpaste contained NaF concentration10, 20 and 40 mg/L. Methods:The tissue block of artificial body root was
prepared from bovine incisor, "open window" and put them in 37 ℃ demineralization solution for 96 hours to form artificial root caries.
Six samples were randomly divided into each group. The demineralized samples were pH-cycled through for 8 days with 6 cycles per
day. The samples were evaluated by using polarized light microscope(PLM). Results:Fluoride toothpaste group showed varying
degrees of mineral deposition, and the deposition band width order was as follow: Darlie>Cnice>Colgate. The deposition band width
order of fluoride-free toothpaste with NaF was as follow: 40 mg/L>20 mg/L>10 mg/L. Conclusion:The remineralization effect of
Darlie in fluoride toothpaste was the best, and the remineralization of fluoride-free toothpaste with 40 mg/L NaF was the best.

Key words: fluoride toothpaste, root caries, remineralization, polarized light microscope

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