大理大学学报 ›› 2021, Vol. 6 ›› Issue (4): 27-29.

• 药学 • 上一篇    下一篇

药学服务指导后肺结核患者用药依从性影响因素分析

陈永刚,罗 季,彭江丽,刘 幸,李 娜,陈 洁   

  1. (大理大学第六附属医院,昆明 650041)
  • 收稿日期:2019-05-05 修回日期:2019-12-31 出版日期:2021-04-15 发布日期:2021-05-19
  • 通讯作者: 陈洁,主任药师,E-mail:chenjie_0222@163.com。
  • 作者简介:陈永刚,副主任药师,主要从事药理学及临床药学研究。
  • 基金资助:
    昆明市科技计划项目(2019-1-S-25318000001154);昆明市卫健委卫生科研课题项目(2020-13-01-112)

Analysis of Factors Influencing Medication Compliance of Patients with Pulmonary Tuberculosis under Pharmaceutical Care Guidance#br#

Chen Yonggang , Luo Ji, Peng Jiangli, Liu Xing, Li Na, Chen Jie   

  1. (The Sixth Affiliated Hospital of Dali University, Kunming 650041, China)
  • Received:2019-05-05 Revised:2019-12-31 Online:2021-04-15 Published:2021-05-19

摘要: [摘要]目的:探究影响肺结核患者用药依从性的危险因素。方法:针对肺结核患者实施全程药学服务指导并建立调查问
卷,对 367份有效问卷患者的基本信息、治疗情况、不良反应等影响用药依从性的因素进行统计分析。结果:纳入研究的
367例患者中,238例(占64.85%)依从性较好,129例(占35.15%)依从性较差。对疾病的认知程度和高尿酸血症是用药依从
性的独立危险因素。结论:肺结核患者用药依从性受多种因素影响,经药学干预后,对疾病的认知程度、是否出现不良反应
(高尿酸血症)仍然是用药依从性最主要的影响因素。药师针对肺结核患者进行个体化药学服务,可显著提高其用药依从
性,增强治疗效果。

关键词: [关键词]药学服务指导, 肺结核, 依从性, Logistic回归分析, 影响因素

Abstract: 〔Abstract〕Objective: To explore the risk factors affecting medication compliance of patients with pulmonary tuberculosis. Methods:
The guidance of whole-course pharmaceutical care was given to tuberculosis patients and a questionnaire was established. The basic
information, treatment status, adverse reactions and other factors affecting medication compliance of 367 valid questionnaires were
statistically analyzed. Results: Among the 367 patients included in the study, 238 patients(64.85%)had good compliance and
129 patients(35.15%)had poor compliance. Awareness of the disease and hyperuricemia were independent risk factors for medication
compliance. Conclusion: Medication compliance of patients with pulmonary tuberculosis is affected by many factors. After
pharmaceutical intervention, the knowledge of the disease and the occurrence of adverse reactions(hyperuricemia)are still the most
important factors influencing medication compliance. Individualized pharmaceutical services provided by pharmacists for tuberculosis
patients can significantly improve their medication compliance and enhance the treatment effect.

Key words: 〔Key words〕pharmaceutical care guidance, pulmonary tuberculosis, compliance, Logistic regression analysis, influence factors

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