大理大学学报 ›› 2021, Vol. 6 ›› Issue (4): 67-70.

• 预防医学 • 上一篇    下一篇

昆明市输入性登革热流行特征及病程相关性分析

 刘 冰,何 花,张燕玲,黄 瑛   

  1. (1.大理大学公共卫生学院,云南大理 671000;2.昆明市第三人民医院,昆明 650041)
  • 收稿日期:2021-01-12 修回日期:2021-03-16 出版日期:2021-04-15 发布日期:2021-05-19
  • 通讯作者: 黄瑛,主任医师,E-mail:hyxanni6@sina.com。
  • 作者简介:刘冰,硕士研究生,主要从事感染性疾病研究。

Correlative Analysis of the Epidemiological Characteristics and Course of Imported Dengue Fever in Kunming#br#

 Liu Bing, He Hua, Zhang Yanling, Huang Ying   

  1. (1. College of Public Health, Dali University, Dali, Yunnan 671000, China; 2. The Third People′s Hospital of Kunming,
    Kunming 650041, China)
  • Received:2021-01-12 Revised:2021-03-16 Online:2021-04-15 Published:2021-05-19

摘要: [摘要]目的:通过对昆明市输入性登革热相关资料分析,为登革热的早期诊疗及防控提供理论依据。方法:收集登革热核
酸阳性患者的相关资料,描述其流行病学特征,并将病程与实验室检查指标进行相关性分析。结果:收集登革热核酸阳性患
者共143例,男101例(70.63%),女42例(29.37%);患者平均年龄为(34.72±9.79)岁;5—12月均有病例报告;来源于柬埔寨91
例(63.64%)。患者主要临床表现为发热 143 例(100.00%),肌肉酸痛 123 例(86.01%),咽充血 109 例(76.22%),头痛 107 例
(74.83%),乏力88例(61.54%);实验室检查结果:白细胞减少96例(67.13%),天冬氨酸氨基转移酶(AST)升高87例(60.84%),
C反应蛋白(CRP)升高74例(51.75%)。病程与白细胞、血小板(PLT)、总胆红素、间接胆红素、γ-谷氨酰转移酶(GGT)、AST相
关性有统计学意义(P<0.05)。结论:昆明市登革热以境外输入、普通登革热感染为主,病程与总胆红素、间接胆红素、GGT、
AST为正相关,与白细胞、PLT为负相关。

关键词: [关键词]登革热, 临床特征, 实验室检查, 病程, 相关性

Abstract: 〔Abstract〕Objective: To provide a theoretical basis for the early diagnosis, treatment, prevention and control of dengue fever based
on an analysis of the relevant data of imported dengue fever in Kunming City. Methods: Data were collected from patients with dengue
fever, the epidemiological characteristics were described, and the correlation between the course of disease and laboratory examination
indicators was analyzed. Results: There were a total of 143 patients with 101 males(70.63%)and 42 females(29.37%), with an
average age of(34.72±9.79)years. Cases were reported from May to December. 91 patients(63.64%)were from Cambodia. The main
clinical manifestations were fever in 143 cases(100.00%), muscle soreness in 123 cases(86.01%), pharyngeal congestion in 109
cases(76.22%), headache in 107 cases(74.83%)and fatigue in 88 cases(61.54%). Laboratory results: 96 patients had leukopenia
(67.13%), aspartate aminotransferase(AST)increased in 87 patients(60.84%), and C-reactive protein(CRP)increased in 74
patients(51.75%). The course of the disease was significantly correlated with white blood cells, platelets(PLT), total bilirubin,
indirect bilirubin, gamma-glutamine transferase(GGT)and AST(P < 0.05). Conclusion: Dengue fever in Kunming is mainly
imported from abroad and infected by common dengue fever. The course of the disease is positively correlated with total bilirubin,
indirect bilirubin, GGT and AST, but it is negatively correlated with white blood cells and PLT.

Key words: 〔Key words〕dengue fever, clinical features, laboratory tests, course of disease, correlation

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