J4 ›› 2011, Vol. 10 ›› Issue (12): 57-59.
目的：探讨AT-III水平与急性冠脉综合征的相关性。方法：选择ACS 患者53 例，分AMI 组42 例和UA 组11 例，与60
例健康体检者进行对照，测定AT-III：Ag 含量，进行对比研究。结果：ACS的AT-芋水平明显低于对照组，而AMI 组较UA组的AT-III水平低，且有统计学意义（P<0.05）。ACS 患者治疗后AT-芋水平增高。结论：ACS 患者AT-芋水平降低，甚至与冠状动脉病变程度成正比，测定其水平有助于反映体内高凝状态，判断疾病预后，进行用药疗效评估。
Objective: To explore the relationship between antithrombin III and acute coronary syndrome （ACS）. Methods: Fiftytwo consecutive patients with ACS were enrolled in the study, 42 cases were acute myocardial infarction （AMI）, and 11 cases were unstable angina （UA）, and 60 healthy subjects were chosen as controls. The plasma level of antithrombin III was measured in all subjects. Results: The levels of antithrombin III in ACS patients group was significantly lower compared to the healthy control; and the patients with AMI showed lowest levels of antithrombin III. The levels of antithrombin III increased significantly after comprehensive treatment of ACS. Conclusion: Plasma levels of antithrombin III decreased in ACS patients. The measurement of antithrombin III could be a reflection of hypercoagulation state, and it is helpful in prognosis and treatment.
