Excel在残数法计算药物动力学参数中的应用

J4 ›› 2011, Vol. 10 ›› Issue (2): 13-15.

Excel在残数法计算药物动力学参数中的应用

大理学院药学院，云南大理 671000

收稿日期:2010-12-23 出版日期:2011-02-15 发布日期:2011-02-15
作者简介:缪菊连，讲师，主要从事药物学研究.

The Application of the Software Excel to Process the Parameters of Pharmacokinetics

College of Pharmacy, Dali University, Dali, Yunnan 671000, China

Received:2010-12-23 Online:2011-02-15 Published:2011-02-15

摘要/Abstract

摘要：

目的：探求残数法计算药物动力学参数的简单方法。方法：采用Excel对数据进行线性回归，得出曲线方程，根据截距和
斜率计算K及Ka。结果：利用Excel能正确、快速计算出K及Ka值。结论：将Excel应用残数法计算K及Ka值能减少工作量，提高准确率及工作效率。

关键词: Excel, 残数法, 药物动力学

Abstract:

Objective：To search a convenient way for processing the parameters of pharmacokinetics. Methods：The software Excel was applied to analyze pharmacokinetics data to draw the curve, obtain curve equation, and calculate the parameters of K and Ka according to slope and intercept. Results：The software Excel was an efficient and exact way to process the parameters of K and Ka. Conclusion：Using software Excel to process the pharmacokinetics parameters could reduce workload; improve accuracy and efficiency of data analysis.

Key words: Excel, data analysis, pharmacokinetics

中图分类号:

R969.1

缪菊连. Excel在残数法计算药物动力学参数中的应用[J]. J4, 2011, 10(2): 13-15.

MIAO Ju-Lian. The Application of the Software Excel to Process the Parameters of Pharmacokinetics[J]. J4, 2011, 10(2): 13-15.

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