J4 ›› 2014, Vol. 13 ›› Issue (4): 1-3.

• 药学 •    下一篇

线纹香茶菜地下部分化学成分研究

  

  1. 大理学院药学与化学学院,云南大理 671000
  • 收稿日期:2013-12-13 修回日期:2014-01-08 出版日期:2014-04-15 发布日期:2014-04-15
  • 作者简介:孙俊哲,硕士研究生,主要从事药物化学研究.
  • 基金资助:

    国家自然科学基金资助项目(81060259);云南省百名海外高层次人才引进计划基金资助项目(云组通〔2011〕123号)

Chemical Constituents from Underground Part of Isodon lophanthoides

  1. College of Pharmacy and Chemistry,Dali University,Dali,Yunnan 671000,China
  • Received:2013-12-13 Revised:2014-01-08 Online:2014-04-15 Published:2014-04-15

摘要:

目的:研究线纹香茶菜地下块状根茎的化学成分。方法:用70%丙酮冷浸提取,相关部位的主要成分通过硅胶柱层析分
离纯化,依据现代波谱技术及与标准品对照的方式进行结构鉴定。结果:由乙酸乙酯部位分离得到6个化合物,分别鉴定为β-谷甾醇(1),3 β-乙酰基齐墩果酸(2),3 β-乙酰基乌苏酸(3),油酸(4),花柏酚(5),山楂酸(6)。结论:上述成分均为首次从该植物地下块状根茎中分离,其中2~6为首次由该植物中获得。

关键词: 线纹香茶菜, 地下块状根茎, 萜类化合物

Abstract:

Objective:To explore the chemical constituents of tuber of Isodon lophanthoides. Methods:Compounds were separated and purified by silica gel column chromatography and their structures were elucidated on the basis of spectral analysis and chemical evidences. Results:Six constituents were isolated from ethyl acetate fraction of the extract and identified as β-sitosterol(1),3β-Oacetyloleanolic acid (2),3β-O-acetylursolic acid (3),oleic acid (4),hinokiol (5),and 2 -hydroxyloleanolic acid(6). Conclusion:Compounds 1-6 are isolated from the underground part of I. lophanthoides for the first time,while 2-6 are firstly obtained from this plant as well.

Key words: Isodon lophanthoides, tuber, constituents

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