楚雄地区1970例变应性鼻炎吸入性变应原谱分析

J4 ›› 2015, Vol. 14 ›› Issue (10): 36-38.

楚雄地区1970例变应性鼻炎吸入性变应原谱分析

（大理大学楚雄附属医院，云南楚雄675000）

收稿日期:2014-08-26 出版日期:2015-10-15 发布日期:2015-10-15
作者简介:刘晖，副主任医师，主要从事耳鼻咽喉头颈外科研究.

Inhalation Allergen Spectrum Analysis of 1970 Cases of Allergic Rhinitis in Chuxiong

(Affiliated Hospital of Dali University in Chuxiong, Chuxiong, Yunnan 675000, China)

Received:2014-08-26 Online:2015-10-15 Published:2015-10-15

摘要/Abstract

摘要：

目的:探讨楚雄地区变应性鼻炎（AR）患者吸入性变应原谱分布情况。方法：对近5年门诊1 970例疑似AR患者进行吸
入性变应原皮肤点刺试验（SPT），其中男性887例，女1 083例，分析比较变应原分布特点。结果：吸入性变应原SPT总阳性率
为83.05%（1 636 例）；SPT 阳性率前5 位的变应原分别为户尘螨（68.12%）、粉尘螨（64.11%）、蟑螂（41.22%）、蒿属花粉
（40.66%）、法国梧桐（40.10%）。吸入性变应原阳性级别（++）及以上的患者中，粉尘螨和户尘螨分别占两者的79.02%和
81.52%为最高，明显高于其他变应原。不同年龄组之间随年龄增长，总阳性率逐渐下降，差异具有统计学意义（χ2=33.25，P<0.01）。
结论：粉尘螨、户尘螨、蟑螂、蒿属花粉、法国梧桐是楚雄地区主要的吸入性变应原。

关键词: 鼻炎, 变应性, 变应原, 皮肤点刺试验

Abstract:

Objective：To explore the spectrum distribution of inhale allergen in patients with allergic rhinitis (AR) in Chuxiong
region. Methods: Inhaled allergen skin prick test (SPT) was conducted to 1 970 clinic patients with suspected AR treated in recent five
years in Chuxion, among which 887 were male, 1 083 were female cases. Allergen distribution characteristics were comparatively
analyzed. Results: Total positive rate ofiInhalation allergen SPT was 83.05% (1 636 cases); Five allergens ranked top in the SPT
positive rate were respectively the household dust mites (68.12%), dust mite (64.11%), cockroach (41.22%), artemisia pollen (40.66%),
and platanus (40.10% ). In inhaled allergens positive level (++ ) and above patients, dust mites and household dust mites were
respectively 79.02% and 81.52%, which ranked the top two and were significantly higher than other allergens. In different age groups,
the total positive rate fell with the increase of age, which had statistically significant difference ( χ2 =33.25,P <0.01). Conclusion: Dust
mites, dust mites, roaches, artemisia pollen, platanus were the main inhaled allergens in Chuxiong region.

Key words: rhinitis, allergic, allergens, skin prick test

中图分类号:

R765.21

刘晖，李惠华，张美玲. 楚雄地区1970例变应性鼻炎吸入性变应原谱分析[J]. J4, 2015, 14(10): 36-38.

Liu Hui, Li Huihua, Zhang Meiling. Inhalation Allergen Spectrum Analysis of 1970 Cases of Allergic Rhinitis in Chuxiong[J]. J4, 2015, 14(10): 36-38.

参考文献

〔1〕Strachan D，Sibbald B，Weiland S，et al. Worldwide varia?
tions in prevalence of symptoms of allergic rhinoconjunctivi?
tis in children：the International Study of Asthma and Aller?
gies in Childhood（ISAAC）〔J〕. Pediatr Allergy Immunol，
1997，8：161-168.
〔2〕韩德民，张罗，黄丹，等. 我国11个城市变应性鼻炎自报
患病率调查〔J〕.中华耳鼻咽喉头颈外科杂志，2007，42
（5）：378-384．
〔3〕中华耳鼻咽喉头颈外科杂志编委会，中华医学会耳鼻咽
喉头颈外科鼻科学组.变应性鼻炎诊断和治疗指南〔J〕.
中华耳鼻咽喉头颈外科杂志，2009，44（12）：977-978．
〔4〕杨彩虹，高静.厦门地区变应性鼻炎患者变应原皮肤点
刺实验结果分析〔J〕.中国耳鼻咽喉头颈外科，2014，21
（2）：78-80.
〔5〕Malling H. Immunotherapy. Position paper of the European
Academy of Allergy and Clinical mmunology〔J〕. Allergy，
1993，48（s14）：9-35.
〔6〕张淑萍，曲政海.变态反应性疾病的诊断〔M〕/曲政海，
高美华. 儿童变态反应病学. 北京：人民卫生出版社，
2006：215-240.
〔7〕刘晓宇，吴捷，王斌，等.中国不同地理区域室内尘螨的
调查研究〔J〕.中国人兽共患病学报，2010，26（4）：310-
314.
〔8〕杨艳，张文君，李薇，等.广州地区1335例变态反应性皮
肤病患者变应原分析〔J〕.皮肤性病治疗学杂志，2010，
17（5）：361-365.
〔9〕薄涛，徐丽阳，鲁晶，等.包头地区498例变应性鼻炎变应
原筛查与分析〔J〕.中国中西医结合耳鼻咽喉杂志，2009，
17（2）：115-116.
〔10〕孙宝清，李靖，钟南山.全国多中心支气管哮喘与过敏
性鼻炎门诊患者对蟑螂变应原皮肤反应性的调查〔J〕.
中华哮喘杂志，2009，3（1）：27-29．
〔11〕Akerman M，Valentinem S，Rao M，et al. Allergen sensitiv?
ity and asthma severity at an inner city asthma center〔J〕.
J Asthma，2003，40（1）：55-62.
〔12〕Montealegre F，Meyer B，Chardon D，et al. Comparative
prevalence of sensitization to common animal，plant and
mould allergens in sbjects with asthma，or atopic dermatitis
and/or allergic rhinit is living in a tropical environ?
ment〔J〕. Clin Exp Allergy，2004，34（1）：51-58.
〔13〕林有润.中国植物志〔M〕. 北京：科学出版社，1991：1-3.