Abstract:

Objective: To understand the distribution of IgG anti-D-positive among voluntary blood donors with Rh（D）-negative
with screen testing in Dali Prefecture. Methods: IgM+IgG anti-D serum were used to test voluntary donors blood samples from January
2009 to July 2014. 241 Rh（D）-negative donors were preliminary screened as negative samples from 153 826 donors, and Rh（D）
phenotype were further tested with three different batches of IgG anti-D serum. Results: 11 samples were tested as weak D serological
phenotype（Rh（Du））. The proportions of weak D phenotype among the voluntary blood donors of all nationalities were 0.010% in the
Han nationality, 0.004% in the Bai nationality, and 0.005% in the Yi nationality. No weak D phenotype was detected in other
nationalities because of the small number of people. Serological phenotype included CcDuee, ccDuee, CCDuee, and ccDuEe. The
Distribution of ABO blood type of weak D phenotype donors was B＞O＞A＞AB. Conclusion：Among the Rh（D）-negative voluntary
blood donors in Dali Prefecture, there are donors with weak D phenotype in varying degree.

Key words: blood donors, Rh（D）-negative, weak D phenotype