Abstract: Objective: To explore the clinical efficacy of Shiwei Wendan Decoction combined with western medicine in the treatment
of hypertension accompanied by insomnia. Methods: A total of 60 patients diagnosed with phlegm dampness internal resistance type
hypertension accompanied by insomnia at the outpatient clinic of the First Affiliated Hospital of Guizhou University of Traditional
Chinese Medicine from January 2023 to January 2024 were enrolled in the study. Patients were divided into a contrd group and an
experiment group according to random number table method, with 30 cases in each group. The control group received nifedipine control
release tablets combined with estazolam tablets, while the experimental group received nifedipine control release tablets combined with
Shiwei Wendan Decoction. Changes in blood pressure, Pittsburgh sleep quality index （PSQI） scores, Traditional Chinese Medicine
（TCM） syndrome scores, efficacy, and adverse reactions before and after treatment were compared between the two groups. Results:
After treatment, both groups showed significant reductions in blood pressure, PSQI scores, and TCM syndrome scores compared to
before treatment. The experimental group showed greater improvement in all these indicators compared to the control group. The total
effective rate in the experimental group was significantly higher than that in the control group, with statistically significant differences
（P<0.05）. The incidence of adverse reactions in both groups was 3.33%, with no significant difference （P>0.05）. Conclusion: Shiwei
Wendan Decoction demonstrates a remarkable clinical efficacy with fewer adverse reactions, making it effective in improving insomnia
symptoms in patients with hypertension.

Key words: Shiwei Wendan Decoction, hypertension, insomnia, clinical efficacy