Abstract: After the studies are conducted and problems existing in applications of hydrophobically associating watersoluble polymers(HAWP) have been discussed, it is concluded that all these problems in different aspects are the result of incorrect molecular design and inexact control during polymerization process. The relationship between hydrophobical interaction and properties of HAWP, as well as effects of temperature and salt on HAWP solution, are studied, a new idea about HAWP molecular design is put forward that intra/intermolecular association can be tuned by rationally choosing spacer and chemical bond between main chain and its hydrophobic contents. This new method is named as HAWP molecular design with highratio intermolecular association. The object of highratio intermolecular association molecular design is to furtherly improve temperature tolerance and salt resistance ability of HAWP and decrease sideeffect of hydrophobic contents as well.

Key words: hydrophobically associating watersoluble polym, molecular design, intra and intermolecular association, hydrophobical interaction, mechanisms of hydrophobical association