Abstract:

Objective: To understand the clinical infection and drug resistance of enterococcal patients in our hospital in recent two
years and provide a better basis for clinical medication. Methods: VITEK 2 Compact was used for bacterial identification and drug sensitivity test, K-B method for drug sensitivity test and data analysis. Results: 116 strains of Enterococcus faecium and 78 strains of Enterococcus faecalis from the urine, secretions and sputum were detected. The overall resistance rate in Enterococcus faecium was significantly higher than that in the Enterococcus faecalis. In the subjects of antimicrobial agents, the drug resistence rate of Enterococcus to tigecycline was zero, followed by linezolid and vancomycin. Conclusion: Clinically, the main infections of Enterococcus were the feces and the fecal. The drug resistance rate of Enterococcus faecium to most of the antibiotics was higher than that of the Enterococcus faecalis. Tigecycline, linezolid and vancomycin were the most sensitive antibactarials to Enterococcus, but there has been Enterococcus resistant to vancomycin and linezolid. The clinical detection of Enterococcus should be strenghtened to reduce the generation of drug-resistant strains.

Key words: Enterococcus, clinical infection, antibiotics, drug resistance