Analysis of Clinical Distribution and Drug
Resistance Trend of Klebsiella pneumoniae in Hospital A from 2018 to 2020

Abstract

Abstract: Objective： To analyze the clinical distribution and drug resistance trend of Klebsiella pneumonia（KP） in a tertiary hospital A in Dali from 2018 to 2020， in order to provide experimental evidence for clinical treatment. Methods： The specimens submitted for clinical examination in this hospital from 2018 to 2020 were isolated and cultured， strain identification and drug susceptibility test were conducted， and the clinical distribution and drug resistance trend of KP were retrospectively analyzed. Results： From 2018 to 2020， a total of 1 642 KP strains were isolated， including 218 strains of ESBL- Klebsiella pneumoniae （ESBL-KP） and 56 strains of carbapenems-resistant KP（CR-KP）. The main department source of KP and ESBL-KP was pediatrics， and the main department source of CR-KP was the intensive care unit （ICU）. The drug susceptibility results showed that ESBL-KP had extremely high resistance to β-lactam antibacterials， but no resistance to carbapenems had been found. CR-KP was highly resistant to three-quarters of the antibacterial drugs in the susceptibility test. Conclusion： Facing the problem of increasing resistance to KP， clinical departments should be vigilant and send patient specimens for examination in time. At the same time， medical staff should strengthen self-protection， prevent cross-infection among patients， and strengthen the rational use of antibiotics.

Key words: font-family:SimSun, ">Klebsiella pneumoniaefont-family:SimSun, ">；font-family:SimSun, "> resistance ratefont-family:SimSun, ">；font-family:SimSun, "> ESBL-KPfont-family:SimSun, ">；font-family:SimSun, "> CR-KP

CLC Number:

Fan Yujuan, Ma Yanan, Wang Li, Li Fuxing, Zhang Yulin, Cheng Mingjing, Zhao Weidong.

Analysis of Clinical Distribution and Drug Resistance Trend of Klebsiella pneumoniae in Hospital A from 2018 to 2020 [J]. Journal of Dali University, 2022, 7(2): 62-66.

References

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Analysis of Clinical Distribution and Drug Resistance Trend of Klebsiella pneumoniae in Hospital A from 2018 to 2020

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