Study on the Chemical Constituents of
Chloroform Extract from Medicinal Insect Vespa auraria

Abstract

Abstract:

Objective： To study the chemical constituents of medicinal insect Vespa auraria. Methods： The monomer compounds were obtained by the methods of chromatographic separations and purification， and the structures of compounds were identified by carbon and hydrogen NMR data analysis combined with literature comparison. Results： Eleven compounds were isolated and identified from the chloroform extract of Vespa auraria， including five cyclic dipeptides： cyclo（Ala-Pro）（1）， cyclo（Pro-Pro）（2）， cyclo（Pro-Gly）（3）， cyclo（Pro-Tyr）（4）， cyclo（Thr-Pro）（5）， one acetylated amino acid： N-acetyl-isoleucine（6）， one organic amine： N-acetyl-4-（4-hydroxybenzene）ethylamine（7）， and three small molecule heterocyclic acids： nicotinic cacid（8）， 1-methyl-1，2，3，4-tetrahydro-carboline-3-carboxylic acid（9）， 3-indoleacetic acid（10）， and one benzodioxane compound：（2R，3S）-2-（3'，4'-dihydroxyphenyl）-3-acetylamino-7-（N-acetyl-2''-aminoethyl）-1，4-benzodioxane（11）. Conclusion： All the eleven compounds are isolated from this medicinal insect for the first time.

Key words: Vespa auraria, medicinal insect, chemical constituent

CLC Number:

R284.1

Huang Yanmin, Pang Xiuqin, Xu Jinglei, Tang Songyuan, Li Yongjian, Yang Zhibin, Xiao Huai.

Study on the Chemical Constituents of Chloroform Extract from Medicinal Insect Vespa auraria [J]. Journal of Dali University, 2022, 7(8): 1-5.

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Study on the Chemical Constituents of Chloroform Extract from Medicinal Insect Vespa auraria

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