The Prognostic Value of NLR and PLR in Patients with Maintenance Hemodialysis

Abstract

Abstract:

Objective： To explore the prognostic value of neutrophil-lymphocyte ratio（NLR） and platelet-lymphocyte ratio （PLR） in patients with maintenance hemodialysis（MHD）. Methods： Medical records of 119 patients who underwent MHD treatment at Baoshan People's Hospital from January 2017 to October 2020 were collected， and the patients were grouped according to the median PLR and NLR， and the clinical data of each group were evaluated. Kaplan-Meier survival curve was used to analyze all-cause mortality rates in the NLR and PLR groups. COX regression models were used to analyze the risk factors for all-cause mortality in the patients. The predictive value of NLR for all-cause mortality in MHD patients was evaluated using receiver operator characteristic（ROC） curve. Results： In the PLR group， there were no significant differences in laboratory parameters and all-cause mortality rates between the two groups（P>0.05）. In the NLR group， there were significant differences in albumin， hypersensitive C-reactive protein （hsCRP）， single-pool urea clearance rate， and all-cause mortality rates between the two groups （P<0.05）. The adjusted COX regression model showed that the increasing age， elevated NLR， hsCRP and decreased single-pool urea clearance rate were independent predictors of all-cause mortality rate. The ROC curve analysis showed that the area under the curve for NLR in predicting all-cause mortality in MHD patients was 0.716（95%CI： 0.598-0.833）， with a sensitivity of 78.30% and specificity of 64.60%. Conclusion： NLR can independently predict the prognosis of MHD patients.

Key words:

neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, maintenance hemodialysis, prognosis

CLC Number:

R572.2 ','1');return false;" target="_blank">
R572.2

Li Chunyan.

The Prognostic Value of NLR and PLR in Patients with Maintenance Hemodialysis [J]. Journal of Dali University, 2023, 8(10): 76-80.

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