大理大学学报 ›› 2021, Vol. 6 ›› Issue (8): 31-34.DOI: 10. 3969 / j. issn. 2096-2266. 2021. 08. 006

• 药学 • 上一篇    下一篇

252 例住院患者注射用头孢他啶临床应用合理性评价

卜 伟,王玉和,龚 磊*   

  1. (遵义医科大学附属医院药剂科,贵州遵义 563003)
  • 收稿日期:2020-06-10 修回日期:2020-06-29 出版日期:2021-08-15 发布日期:2021-09-28
  • 通讯作者: 龚磊,主任药师,E-mail:312331819@qq.com。
  • 作者简介:卜伟,主管药师,博士,主要从事临床合理用药研究。
  • 基金资助:
    贵州省遵义市科技计划项目(遵义科合HZ 字(2020)251 号)

Evaluation of Rational Clinical Application of Ceftazidime for Injection in 252 Inpatients

Bu Wei, Wang Yuhe, Gong Lei*   

  1. (Department of Pharmacy, The Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou 563003, China)
  • Received:2020-06-10 Revised:2020-06-29 Online:2021-08-15 Published:2021-09-28

摘要: 目的:评价头孢他啶临床用药的合理性,为临床规范、合理使用头孢他啶提供参考。方法:回顾性研究遵义医科大学
附属医院(以下简称“我院”)2019 年7 月至2019 年9 月252 例应用注射用头孢他啶的住院患者病例,从适应证、给药方案、
微生物送检率、联合用药等方面进行合理性评价。结果:我院注射用头孢他啶的药物利用指数(DUI)<1;252 例病例中,用
药合理214 例(84.92%),不合理38 例(15.08%);微生物送检146 例(57.94%),主要为血液标本84 例(57.53%),痰液
标本42 例(28.77%);两种药物联合使用67 例(26.59%),1 例存在配伍禁忌(0.40%)。应用注射用头孢他啶的患者主要集
中在呼吸与危重医学病区,涉及病种主要为肺炎、哮喘等呼吸道疾病,共71 例(28.18%)。结论:我院注射用头孢他啶使用
基本合理,但仍存在部分用药不适宜的情况。

关键词: 住院患者, 注射用头孢他啶, 用药合理性

Abstract: Objective: To evaluate the rationality of clinical use of ceftazidime and to provide reference for clinical standardization
and rational use of ceftazidime. Methods: A total of 252 hospitalized patients who received ceftazidime injection were selected from
July 2019 to September 2019 in the Affiliated Hospital of Zunyi Medical University (hereinafter referred to as “our hospital”). The
rationality of medication was evaluated in terms of indications, dose regimen, microbiological examination, and combination of drugs.
Results: The drugs of utilization index (DUI) of ceftazidime for injection in our hospital was < 1. Among the drug use of 252 cases,
214 cases (84.92%) were rational and 38 cases (15.08%) were irrational; 146 cases (57.94%) received routine etiological examinations,
including 84 blood samples (57.53%) and 42 sputum samples (28.77%); 67 cases (26.59%) received combined use of the two drugs,
and 1 case (0.40%) was incompatible. The patients used ceftazidime for injection were mainly hospitalized in the respiratory and critical
medical area, involving respiratory diseases such as pneumonia and asthma, with a total number of 71 cases (28.18%). Conclusion: The
clinical use of ceftazidime for injection in our hospital is basically rational, but there were still a few cases with inappropriate drug use.

Key words: inpatient, ceftazidime for injection, rational use of drug

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