外周血白细胞计数与冠心病

J4 ›› 2011, Vol. 10 ›› Issue (2): 30-32.

外周血白细胞计数与冠心病

大理学院附属医院，云南大理 671000

收稿日期:2010-06-18 出版日期:2011-02-15 发布日期:2011-02-15
作者简介:李利华，讲师，主要从事心血管疾病研究.
基金资助:
国家自然科学基金资助项目（30960137）

Association between Peripheral Leucocyte Count and Coronary Heart Disease

Affiliated Hospital of Dali University, Dali, Yunnan 671000，China

Received:2010-06-18 Online:2011-02-15 Published:2011-02-15

摘要/Abstract

摘要：

目的：研究外周血白细胞计数及其亚群与冠脉病变之间的关系。方法：收集本院2009年3月至2010年5月所有进行冠脉造
影患者的相关数据，并进行统计分析。结果：和冠脉造影正常者（n=20）相比，冠心病患者（n=52）外周血白细胞计数、中性粒细胞计数、中性粒细胞比例、中性/淋巴细胞比例显著升高，淋巴细胞比例显著降低（P≤0.03）。对冠脉病变范围与白细胞计数及其亚群的分析发现，与冠脉无病变者相比，冠脉病变者外周血白细胞计数、中性粒细胞计数、中性粒细胞比例、中性/淋巴细胞比例显著升高，淋巴细胞比例显著降低（P≤0.02）。结论：外周血白细胞计数及分类可能有助于预测冠状动脉病变及其严重程度。

关键词: 白细胞计数, 冠脉造影, 冠脉病变

Abstract:

Objective: To investigate the relationship between peripheral leucocyte count and coronary atherosclerosis disease.
Method: The data of 72 patients who received coronary angiography for the first time during March 2009 and May 2010 were collected and analyzed. Results: The peripheral leucocyte count, neutrophil count, neutrophil proportion, neutrophil/lymphocyte ratio were significantly higher in patients with angiographically abnormal coronary arteries group （n=52）compared with the patients with angiographically normal arteries group （n =20）（P≤0.03）.
However, the lymphocyte proportions were significantly lower in the angiographically abnormal group （P≤0.02）.
Conclusions: Peripheral leucocyte count and classification may predict the lesion and severity of coronary atherosclerosis.

Key words: leucocyte count, coronary artery angiography, coronary atherosclerosis

中图分类号:

R541.4

李利华, 杨瑛, 董榆, 黄修献, 吴新华. 外周血白细胞计数与冠心病[J]. J4, 2011, 10(2): 30-32.

LI Li-Hua, YANG Ying, DONG Yu, HUANG Xiu-Xian, WU Xin-Hua. Association between Peripheral Leucocyte Count and Coronary Heart Disease[J]. J4, 2011, 10(2): 30-32.

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