毛大丁草叶醇提物对大鼠离体子宫的作用

J4 ›› 2013, Vol. 12 ›› Issue (6): 90-92.

• 学生园地 • 上一篇

毛大丁草叶醇提物对大鼠离体子宫的作用

大理学院药学与化学学院，云南大理 671000

收稿日期:2012-08-30 修回日期:2013-04-29 出版日期:2013-06-15 发布日期:2013-06-15
作者简介:柳斌，药学专业2009级本科生.
基金资助:
大理州科技局科研基金资助项目（2060402）；大理学院大学生科研基金资助项目（DXSKYY201123）

In Vitro Study of the Effect of Gerbera piloselloides Ethanol Extract on the Uterus of Rat

College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China

Received:2012-08-30 Revised:2013-04-29 Online:2013-06-15 Published:2013-06-15

摘要/Abstract

摘要：

目的：研究毛大丁草叶醇提物对大鼠离体子宫的作用。方法：取成熟雌性未孕大鼠，用击打法处死，取子宫角制备大鼠离
体子宫段，采用BL-420E+生物机能系统记录子宫张力信号，观察毛大丁草叶醇提物对大鼠离体子宫自发收缩和催产素诱发收
缩的影响。结果：毛大丁草叶醇提物可以使大鼠离体子宫收缩频率减慢、强度减小和活动力减弱。结论：毛大丁草叶醇提物对大
鼠离体子宫自发收缩和催产素诱发收缩均具有明显的抑制作用。

关键词: 毛大丁草叶, 醇提物, 大鼠, 离体子宫

Abstract:

Objective: To investigate the effect of ethanol extract from leaves of Gerbera piloselloides on the uterus of rat in vitro.
Methods: Ten mature female but not pregnant SD rats were executed by strike, and uterine horns were used for the rat uterus
segment in vitro. BL-420E+ Biological Functional System was used to record uterine tension, the effect of Gerbera piloselloides
Ethanol Extract on spontaneous contraction and oxytocin-induced contraction of uterus were recorded. Results: The extract could
slow down the uterine contraction frequency and decrease the contraction intensity, and weaken the uterine motility as well.
Conclusion: The ethanol extract of Gerbera piloselloides has significant inhibitive effect on the spontaneous contraction and oxytocininduced
contraction of rat uterus in vitro.

Key words: Gerbera piloselloides, ethanol extract, rat, uterus in vitro

中图分类号:

R285.5

柳斌, 郭美仙, 刘勇, 陆翠芬, 刘光明, 陈光勇. 毛大丁草叶醇提物对大鼠离体子宫的作用[J]. J4, 2013, 12(6): 90-92.

LIU Bin, GUO Mei-Xian, LIU Yong, LIU Cui-Fen, LIU Guang-Ming, CHEN Guang-Yong. In Vitro Study of the Effect of Gerbera piloselloides Ethanol Extract on the Uterus of Rat[J]. J4, 2013, 12(6): 90-92.

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毛大丁草叶醇提物对大鼠离体子宫的作用

In Vitro Study of the Effect of Gerbera piloselloides Ethanol Extract on the Uterus of Rat

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