J4 ›› 2014, Vol. 13 ›› Issue (2): 6-8.

• 药学 • 上一篇    下一篇

酢浆草对小鼠急性腹膜炎的抗炎镇痛作用研究

  

  1. 大理学院药学与化学学院,云南大理 671000
  • 收稿日期:2013-12-06 修回日期:2013-12-23 出版日期:2014-02-15 发布日期:2014-02-15
  • 作者简介:郭美仙,实验师,主要从事中药药理学研究.

Anti-inflammatory and Analgesic Effects of Oxalis corniculata L. on Acute Peritonitis in Mice

  1. College of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000,China
  • Received:2013-12-06 Revised:2013-12-23 Online:2014-02-15 Published:2014-02-15

摘要:

目的:研究酢浆草对醋酸所致急性腹膜炎小鼠的抗炎镇痛作用。方法:腹腔注射醋酸制备小鼠急性腹膜炎模型,观察
酢浆草乙醇提取物对醋酸所致小鼠扭体反应的影响;观察酢浆草乙醇提取物对醋酸所致小鼠腹腔毛细血管通透性增高的影
响。结果:酢浆草乙醇提取物能使小鼠扭体反应次数减少;能降低小鼠腹腔毛细血管的通透性。结论:酢浆草对醋酸所致小鼠急性腹膜炎具有一定的抗炎镇痛作用。

关键词: 酢浆草, 急性腹膜炎, 抗炎, 镇痛

Abstract:

Objective: To study the analgesic and anti-inflammatory effects of Oxalis corniculata L. on acute peritonitis induced by
acetic acid in mice. Methods: Mice peritonitis model caused by intraperitoneal injection of acetic acid was used to observe the effects of the ethanol extract of Oxalis corniculata L. on the body torsion reaction and the abdominal blood capillary permeability. Results: The ethanol extract of Oxalis corniculata L. reduced the body torsion times and the abdominal capillary permeability of mice inducedby acetic acid. Conclusion: Oxalis corniculata L. showed anti-inflammatory and analgesic effects on acute peritonitis in mice.

Key words: Oxalis corniculata L., acute peritonitis, anti-inflammatory, analgesic

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