大理州Rh（D）阴性无偿献血者血清学表型和不规则抗体的调查

J4 ›› 2014, Vol. 13 ›› Issue (8): 45-46.

大理州Rh（D）阴性无偿献血者血清学表型和不规则抗体的调查

大理州中心血站，云南大理 671000

收稿日期:2014-03-21 出版日期:2014-08-15 发布日期:2014-08-15
作者简介:李剑波，主管护师，主要从事血液学研究.

Investigation of Serological Phenotype and Irregular Antibody among Volunteer Blood Donors of
Rh（D）Negative in Dali Prefecture

Blood Center of Dali Prefecture, Dali, Yunnan 671000, China

Received:2014-03-21 Online:2014-08-15 Published:2014-08-15

摘要/Abstract

摘要：

目的：了解大理州无偿献血者Rh（D）阴性血型的血清学表现型及不规则抗体存在情况。方法：检测献血者样本136 803
例，采用血清学方法确证Rh 表现型，使用抗人球蛋白试剂对不规则抗体作筛查。结果：确证Rh（D）阴性献血者209 例
（0.15%）；其中含不规则抗体1例（0.48%），血清学表现型中：ccdee 123例（58.85%），Ccdee 67例（32.06%），CCdee 7例（3.35%），ccdEe 6例（2.87%），CcdEe 5例（2.39%），CCdEe 1例（0.48%）。该阴性献血者ABO血型分布情况A＞O＞B＞AB。结论：对献血者Rh（D）阴性血型的血清学表现型及不规则抗体作检测，将有利于为临床安全及时有效输血提供保障。

关键词: Rh（D）阴性血型, 表现型, 不规则抗体

Abstract:

Objective: To investigate serological phenotype and to detect irregular antibody among Rh（D）negative blood donors in Dali Prefecture. Methods: 136 803 blood samples were detected to determine the Rh phenotypes through serological tests and the irregular antibodies were screened through antiglobulin tests. Results: 209 blood samples were Rh（D）negative（0.15%）. The irregular antibodies were found in one Rh（D）negative sample（0.48%）. The serological phenotypes included 123 ccdee（58.85%）, 67 Ccdee（32.06%）, 7 CCdee（3.35%）, 6 ccdEe（2.87%）, 5 CcdEe（2.39%）and 1 CcdEe（0.48%）. Among all Rh（D）negative volunteer blood donors, the distribution of A, B, O and AB blood types was A＞O＞B＞AB. Conclusion: The study of serological phenotype and irregular antibody of Rh（D）negative blood donors would be helpful for enhancing the clinical safety and timely blood
transfusion.

Key words: Rh（D）negative blood type, phenotype, irregular antibody

中图分类号:

R331.1

李剑波, 杜月娥, 刁丽波, 蔡云玲, 叶文华, 梁艳娇, 何永勋. 大理州Rh（D）阴性无偿献血者血清学表型和不规则抗体的调查[J]. J4, 2014, 13(8): 45-46.

LI Jian-Bo, DU Yue-E, DIAO Li-Bo, CAI Yun-Ling, YE Wen-Hua, LIANG Yan-Jiao, HE Yong-Xun. Investigation of Serological Phenotype and Irregular Antibody among Volunteer Blood Donors of
Rh（D）Negative in Dali Prefecture[J]. J4, 2014, 13(8): 45-46.