云南昆钢医院2013年三、四季度细菌耐药性监测分析

摘要/Abstract

摘要：

目的：分析云南昆钢医院2013年三、四季度的细菌耐药情况，为临床治疗提供可靠依据。方法：用VITET-2 Compact
全自动微生物分析仪鉴定细菌，采用肉汤微量稀释法做体外药敏试验，依照美国临床实验室标准化协会2013年制定的判断药
敏试验标准。结果：第三、四季度检验科收到标本3 920份，检出致病菌953株，阳性率24.3%。其中排在前5位的病原菌株种
类分别是：大肠埃希氏菌263株、肺炎克雷伯112株、金黄色葡萄球菌56株、铜绿假单胞菌48株、鲍曼不动杆菌41株。药敏大
肠埃希氏菌对复方新诺明、氨苄西林的耐药率分别为93.6%、100.0%，肺炎克雷伯菌对复方新诺明、哌拉西林耐药率分别为
100.0%、96.4%，鲍曼不动杆菌对头孢唑林、复方新诺明耐药率均大于75.0%，金黄色葡萄球菌青霉素P的耐药率为90.3%，未发
现万古霉素耐药的金黄色葡萄球菌，铜绿假单胞菌氨苄西林、头孢唑啉、头孢曲松耐药率均为100.0%。结论：结合昆钢医院细
菌耐药趋势参照抗生素目录及使用指南合理选用抗生素，减少或减缓耐药菌株的产生。

关键词: 细菌, 多重耐药, 耐药监测

Abstract:

Objective: To analyze the bacterial resistance in Yunnan Kungang Hospital in the third and fourth quarter of 2013 and to
provide a solid basis for clinical treatment. Methods: The VITEK-2 Compact system was used to identify bacteria and the drug
sensitivity test was done by the broth microdilution method according to CLSI's 2013 standards for antimicrobial susceptibility testing.Results: 3 920 specimens were received by Department of Laboratory in two quarters and among them, 953 strains of pathogenic bacteria were identified with the positive rate of 24.3%. The top five pathegens were 263 strains of E.coli, 112 strains of Klebsiella pneumoniae, 56 strains of Staphylococcus aureus, 48 strains of Pseudominas aeruginosa and 41 strains of Acinetobacter baumannii. The drug resistance rates of E.coli to selectrin and ampicillin were 93.6% and 100.0%, Klebsiella pneumoniae to selectrin and piperacillin were 100.0% and 96.4%, Acinetobacter baumannii to cefazolin and selectrin were over 75.0%, Staphylococcus aureus to penicillin P was 90.3%，Staphylococcus aureus to vancomycin was not found, Pseudominas aeruginosa to ampicillin, ceftriaxone and cefazolin were all 100.0%. Conclusion: Based on the bacterial resistance tendency in our hospital and by reference to our antibiotic catalogue and their instructions, antibiotics should be chosen properly in order to decrease or retard the production of resistant strains.

Key words: bacteria, multidrug resistance, surveillance of resistance

中图分类号:

R372

杜琼. 云南昆钢医院2013年三、四季度细菌耐药性监测分析[J]. J4, 2015, 14(2): 47-50.

Du Qiong. Surveillance and Analysis of Bacterial Resistance in Yunnan Kungang Hospital in the Third
and Fourth Quarter of 2013[J]. J4, 2015, 14(2): 47-50.

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