我院质子泵抑制剂在预防应激性溃疡中的合理性评价

J4 ›› 2016, Vol. 1 ›› Issue (10): 27-29.

我院质子泵抑制剂在预防应激性溃疡中的合理性评价

（1.大理大学大理教学医院，云南大理671000；2. 大理大学药学与化学学院，云南大理671000）

收稿日期:2015-07-10 修回日期:2016-05-09 出版日期:2016-10-15 发布日期:2016-10-15
作者简介:聂彩霞，药师，主要从事临床药学研究.

Rationality Evaluation of the Prophylactic Use of Proton Pump Inhibitors for Stress Ulcer in Our Hospital

（1. Dali Teaching Hospital of Dali University, Dali, Yunnan 671000, China; 2. College of Pharmacy and Chemistry, Dali University,
Dali, Yunnan 671000, China）

Received:2015-07-10 Revised:2016-05-09 Online:2016-10-15 Published:2016-10-15

摘要/Abstract

摘要：

目的：了解大理市某医院质子泵抑制剂（PPIs）用于预防应激性溃疡（SU）的情况，评价该类药物的用药合理性。方法：
抽取2015年1月神经外科、肝胆外科、普外科、骨科和泌尿外科使用PPIs的患者病历共158份，对PPIs的预防用药指征、用法用
量、溶媒及疗程的合理性进行评价。结果：应用PPIs预防SU的合理率为82.91%，不合理病例总计27 例，不合理率为17.09%。
主要为用药指征、溶媒选择、剂量及疗程不合理，其中无指征用药占不合理用药的41.18%。结论：PPIs预防SU的应用基本合
理，但不合理用药情况仍存在，还需持续改进。

关键词: 质子泵抑制剂, 应激性溃疡, 合理用药

Abstract:

Objective: To investigate the prophylactic use of proton pump inhibitors（PPIs）for stress ulcer（SU）in our hospital and to
evaluate its rationality. Methods: 158 medical records of patients from Departments of Neurosurgery, Hepatobiliary Surgery, General
Surgery, Orthopedics and Urology Surgery with using PPIs in January 2015 were sampled for evaluation of indications in prophylactic
medication, usage and dosage, solvents and course of treatment of PPIs. Results: The reasonable utilization rate of PPIs for prevention SU
was 82.91%, while 27 cases were unreasonable and the unreasonable rate was 17.09 %. The medication indications, choice of solvent,
dosage and course were unreasonable, and no evidence application accounted for 41.18 % of unreasonable drug use. Conclusion: The
application of PPIs in the prevention of SU is basically reasonable, but irrational use of PPIs exists, which needs to be improved.

Key words: proton pump inhibitors, stress ulcer, rational drug use

中图分类号:

聂彩霞，赵启邹，林意菊，邹治木，张兰胜. 我院质子泵抑制剂在预防应激性溃疡中的合理性评价[J]. J4, 2016, 1(10): 27-29.

Nie Caixia, Zhao Qizou, Lin Yiju, Zou Zhimu, Zhang Lansheng. Rationality Evaluation of the Prophylactic Use of Proton Pump Inhibitors for Stress Ulcer in Our Hospital[J]. J4, 2016, 1(10): 27-29.

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