J4 ›› 2016, Vol. 1 ›› Issue (4): 80-82.

• 临床医学 • 上一篇    下一篇

HAART对男男性行为HIV/AIDS患者疗效观察

  

  1. (1.武汉大学基础医学院,武汉430071;2.昆明市第三人民医院,昆明650034)
  • 收稿日期:2014-12-11 出版日期:2016-04-15 发布日期:2016-04-15
  • 作者简介:郭映武,护师,主要从事艾滋病抗病毒治疗研究.

Clinical Observation of HAART in HIV/AIDS Patients of MSM

  1. (1. Pre-clinical College, Wuhan University, Wuhan 430071, China; 2. The Third People's Hospital of Kunming,
    Kunming 650034, China)
  • Received:2014-12-11 Online:2016-04-15 Published:2016-04-15

摘要:

目的:探讨HAART治疗对MSM感染人群的治疗效果。方法:对2006至2013年接受HAART治疗年满18岁且治疗满
1年以上的224例MSM患者,治疗前后免疫重建、病毒载量、性伴/配偶检测情况、安全套的使用频率及接触性伴人数进行统
计。结果:经HAART治疗的MSM患者病毒量比治疗前得到有效控制(病毒载量小于50 copies/mL),CD4+T淋巴细胞计数治
疗后比治疗前有明显的增长,大部分无保护性行为及性伴数下降(P<0.01),差异有统计学意义。结论:有效HAART治疗
及良好的依从性能够使MSM感染者HIV得到有效控制,安全性行为意识增强,在预防和控制HIV通过男男性行为向普通人
群扩散效果显著。

关键词: 高效联合抗反转录病毒治疗, 男男性行为, 人类免疫缺乏病毒/获得性免疫缺陷综合征

Abstract:

Objective: To explore the effectiveness of Highly Active Antiretroviral Therapy(HAART)in men who have sex with men
(MSM). Methods: 224 AIDS adults cases of MSM had been treated with the Highly Active Antiretroviral Treatment from 2006 to 2013
for more than one year, and immune reconstruction, viral load, the HIV test of spouse, the rate of condom using and number of sexual
partners were analyzed statistically before and after treatment. Results: The viral load in the 224 AIDS cases was apparently controlled
(<50 copies/mL)and the level of CD4+ T cell was apparently increased. The unsafe sex rate and the number of sexual partners were
declined(P<0.01). Conclusion: HIV patients of MSM were effectively controlled through HAART and patient compliance, and the
awareness of safe sex of the MSM patients apparently improved, which showed the remarkable effect in prevention and control of HIV
spreading from MSM infected to the general population.

Key words: HAART, MSM, HIV/AIDS

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