PS联合NCPAP在新生儿呼吸窘迫综合征治疗中的价值

J4 ›› 2016, Vol. 15 ›› Issue (2): 38-40.

PS联合NCPAP在新生儿呼吸窘迫综合征治疗中的价值

（大理州妇幼保健院，云南大理671000）

收稿日期:2015-10-23 出版日期:2016-02-15 发布日期:2016-02-15
作者简介:李梅君，副主任医师，主要从事儿科临床研究.

Effect of Pulmonary Surfactant Combined with NCPAP in the Treatment of Neonatal Respiratory Distress
Syndrome

（Maternal and Child Health-Care Hospital of Dali Prefecture, Dali, Yunnan 671000, China）

Received:2015-10-23 Online:2016-02-15 Published:2016-02-15

摘要/Abstract

摘要：

目的：探讨在新生儿呼吸窘迫综合征（NRDS）救治中肺泡表面活性物质（PS）与鼻塞式持续气道正压通气（NCPAP）联合使用的疗效、临床价值。方法：对近1年多来收治的58例NRDS患儿分为PS联合NCPAP治疗组27例、NCPAP组31例进行对照分析。结果：两组治疗后在血气分析、CPAP时间、肺部X线显著改善者占比、住院天数、疗效等观察指标两组间比较差异有统计学意义（P＜0.01）。结论：PS联合NCPAP治疗NRDS疗效显著，能快速改善患儿呼吸功能，降低死亡率，缩短用氧时间和住院时间，减少常规机械通气的应用，在基层医疗条件相对缺乏的情况下值得推广使用。

关键词: 肺泡表面活性物质, NCPAP, 新生儿呼吸窘迫综合征

Abstract:

Objective: To investigate the curative effect and clinical value of combined use of pulmonary surfactant（PS）and nasal
continuous positive airway pressure（NCPAP）in the treatment of neonatal respiratory distress syndrome（NRDS）. Methods: Fiftyeight cases of NRDS last year were divided into PS combined NCPAP group（27）and NCPAP group（31）, the curative effect of the two groups were conducted comparative analysis. Results: The results of blood gas analysis, time of constant positive airway pressure（CPAP）, pulmonary X- ray, hospital days and curative effect rate were significantly different between the two groups（P<0.01）.Conclusion: PS and NCPAP combined treatment has obvious curative effect, which could quickly improve the respiratory function,reduce the mortality rate and the time of oxygen inhalation and hospitalization, as well as the application of conventional mechanical ventilation. The treatment was recommended for use in primary hospital.

Key words: pulmonary surfactant, nasal continuous positive airway pressure, neonatal respiratory distress syndrome

中图分类号:

R722.19

李梅君，张红. PS联合NCPAP在新生儿呼吸窘迫综合征治疗中的价值[J]. J4, 2016, 15(2): 38-40.

Li Meijun, Zhang Hong. Effect of Pulmonary Surfactant Combined with NCPAP in the Treatment of Neonatal Respiratory Distress
Syndrome[J]. J4, 2016, 15(2): 38-40.