大理大学学报 ›› 2019, Vol. 4 ›› Issue (2): 70-.

• 临床医学 • 上一篇    下一篇

腹膜透析患者血清钙磷及全段甲状旁腺素达标率分析研究

赵先,刘丽茹,崔敏,赵美珠,张雨,何敏华   

  1. (1.大理大学临床医学院,云南大理671000;2.大理大学第一附属医院,云南大理671000)
  • 收稿日期:2018-10-15 修回日期:2018-11-27 出版日期:2019-02-15 发布日期:2019-02-15
  • 通讯作者: 何敏华,教授,E-mail:dlhmh@163.com.
  • 作者简介:赵先,硕士研究生,主要从事肾脏风湿免疫研究.

Analysis of the Attainment Rate of Serum Calcium, Phosphorus and Intact Parathyroid Hormone Levels#br# in Peritoneal Dialysis Patients

Zhao Xian, Liu Liru, Cui Min, Zhao Meizhu, Zhang Yu, He Minhua   

  1. (1. Clinical College, Dali University, Dali, Yunnan 671000, China; 2. The First Affiliated Hospital of Dali University,
    Dali, Yunnan 671000, China)
  • Received:2018-10-15 Revised:2018-11-27 Online:2019-02-15 Published:2019-02-15

摘要: [摘要]目的:调查大理大学第一附属医院腹膜透析(PD)患者钙磷及全段甲状旁腺素(iPTH)的达标率,并探讨残余尿量对钙
磷代谢的影响。方法:收集2017年10月至2018年3月期间在大理大学第一附属医院接受PD治疗3个月以上并规律随访的88
例患者的临床资料进行横断面研究。根据K/DOQI标准对血钙、磷和iPTH进行达标率统计,并与国内外研究进行比较。对残
余尿量进行分组,比较组间钙、磷、iPTH的差异。结果:88例PD患者的血钙、磷、iPTH达标率分别为44.3%、40.9%、12.5%,3项
同时达标为4.5%。与其他研究结果相比,钙磷达标率相近,iPTH达标率较低。无尿组(尿量<100 mL/d)血磷、钙磷乘积高于有
尿组(尿量≥100 mL/d)(P<0.05)。结论:PD患者钙磷代谢紊乱及其继发性甲状旁腺功能亢进控制较差,有待于进一步加强。

关键词: [关键词]腹膜透析, 钙, 磷, 全段甲状旁腺素, 达标率

Abstract: 〔Abstract〕Objective: To investigate the attainment rate of calcium, phosphorus and intact parathyroid hormone(iPTH)levels in
peritoneal dialysis(PD)patients from the First Affiliated Hospital of Dali University, and to explore the effect of residual urine volume
on calcium & phosphorus metabolism. Methods: We collected the clinical data of 88 patients from October 2017 to March 2018 who
received PD for more than 3 months and had regular follow-up in our blood purification center and made a cross-sectional study. The
attainment rates of serum calcium, phosphorus and iPTH levels were calculated according to K/DOQI standard, and compared with the
results from the domestic and foreign studies. According to the residual urine volume patients were divided into two groups(urine
volume <100 mL/d for the anuria group, urine volume ≥100 mL/d for the urine group), and then serum calcium, phosphorus and iPTH
levels between the two groups were compared. Results: The proportions of patients who have reached the normal serum calcium,
phosphorus and iPTH concentrations were 44.3%, 40.9% and 12.5%, respectively. 4.5% patients reached all the target levels for
calcium, phosphorus and iPTH. The attainment rates of calcium and phosphorus in our research was similar to the results of other
studies, but the attainment rate of iPTH was comparatively lower. Serum phosphorus and the calcium - phosphate product
concentrations of the patients without urine were higher than those of the urine group(P<0.05). Conclusion: The control of calcium
and phosphorus metabolic disorder and secondary hyperparathyroidism in PD patients in our center is poor, which needs to be further
strengthened.

Key words: 〔Key words〕Peritoneal Dialysis, calcium, phosphorus, intact Parathyroid Hormone, attainment rate