大理大学学报 ›› 2020, Vol. 5 ›› Issue (2): 88-92.DOI: 10. 3969 / j. issn. 2096-2266. 2020. 02. 020

• 临床医学 • 上一篇    下一篇

晚期妊娠妇女血清中α-L-岩藻糖苷酶与血脂的相关性

朱江贤1 ,沈华仙 2 ,姚昔友 1*   

  1. (1.玉溪市人民医院医学检验科,云南玉溪 653100;2.玉溪市中心血站,云南玉溪 653100)
  • 收稿日期:2019-01-02 修回日期:2019-04-02 出版日期:2020-02-15 发布日期:2020-02-15
  • 通讯作者: 姚昔友,检验医师,E-mail:yxy235ym@163.com。
  • 作者简介:朱江贤,主管技师,主要从事临床血液体液检验研究。

Correlation between Serum α-L-Fucosidase and Blood Lipids in Late Pregnant Women

Zhu Jiangxian 1 , Shen Huaxian 2 , Yao Xiyou 1*   

  1. (1. Department of Clinical Laboratory, People′s Hospital of Yuxi City, Yuxi, Yunnan 653100, China; 2. Center Blood Station of
    Yuxi City, Yuxi, Yunnan 653100, China)
  • Received:2019-01-02 Revised:2019-04-02 Online:2020-02-15 Published:2020-02-15

摘要: 目的:探讨妊娠妇女血清α-L-岩藻糖苷酶(AFU)与血脂的变化及二者的相关性,为晚期妊娠妇女高脂血症的诊断提供
指导。方法:研究分为3组,妊娠28周前的早中期妊娠组、妊娠28周及以后的晚期妊娠组和体检为健康的非妊娠组。分别
检测各组妇女的血清 AFU 活性和血脂浓度并用 SPSS 软件分析。结果:与非妊娠组相比,晚期妊娠组 AFU 活性明显升高
(P<0.05),三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白(LDL)、极低密度脂蛋白(VLDL)、载脂蛋白A(ApoA)、载脂蛋白B(ApoB)
明显升高(P<0.05)。晚期妊娠组中,随着孕周的增加,AFU及各血脂TG、TC、LDL、VLDL、ApoA、ApoB逐渐增加,二者具有相关
性(P<0.05,r>0.900)。结论:晚期妊娠妇女血清AFU与血脂均产生变化,二者具有相关性,血清AFU活性可以协助评估晚期
妊娠孕妇的血脂情况。

关键词: 妊娠, &alpha, -L-岩藻糖苷酶, 血脂, 相关性

Abstract: Objective: To investigate the changes of serum α-L-fucosidase(AFU)and blood lipids in pregnant women and the
correlation between the two factors to provide guidance for the diagnosis of hyperlipidaemia in late pregnant women. Methods: The
subjects were divided into three groups: the early and middle pregnancy group before 28th week of gestation, the late pregnancy group
after 28th week of gestation and the healthy non-pregnancy group. Serum AFU and blood lipid concentration were detected in each
group and analyzed by SPSS software. Results: Compared with non-pregnancy group, AFU in late pregnancy group was significantly
higher(P<0.05). Triglyceride(TG), total cholesterol(TC), low density lipoprotein(LDL), very low density lipoprotein(VLDL),
apolipoprotein A(ApoA)and apolipoprotein B(ApoB)were significantly higher(P<0.05). In the late pregnancy group, with the
increase of gestational weeks, AFU and blood lipids such as TG, TC, LDL, VLDL, ApoA and ApoB increased gradually, and there was a
correlation between them(P<0.05, r>0.9). Conclusion: The serum AFU and blood lipid levels of late pregnant women could change,
and there are correlation between serum AFU and blood lipids. Serum AFU can help evaluate the blood lipid level of late pregnant
women.

Key words: pregnancy, α-L-fucosidase, blood lipid, correlation