激光辅助孵化对高龄妇女的冻融胚胎种植潜力的影响

J4 ›› 2016, Vol. 1 ›› Issue (10): 57-60.

激光辅助孵化对高龄妇女的冻融胚胎种植潜力的影响

（1.大理大学临床医学院，云南大理671000；2.大理大学第一附属医院，云南大理671000）

收稿日期:2015-08-18 修回日期:2016-04-29 出版日期:2016-10-15 发布日期:2016-10-15
作者简介:李正伟，硕士研究生，主要从事妇产科学生殖医学研究.
基金资助:
云南省教育厅科学研究基金资助项目（2013C172）

Influence of Laser-assisted Hatching on the Potential of Elderly Women's
Frozen-thawed Embryo Implantation

（1. Clinical College, Dali University, Dali, Yunnan 671000, China; 2. The First Affiliated Hospital of Dali University, Dali, Yunnan 671000, China）

Received:2015-08-18 Revised:2016-04-29 Online:2016-10-15 Published:2016-10-15

摘要/Abstract

摘要：

目的：分析激光辅助孵化技术对高龄妇女冻融胚胎种植潜力的影响。方法：对427例患者，根据年龄、是否辅助孵化进
行分组，比较各组间胚胎种植率及临床妊娠率。结果：＜35岁的患者，两组胚胎种植率AH组高于非AH组、差异有统计学意
义，临床妊娠率无明显差异、差异无统计学意义；而≥35岁的患者，胚胎种植率及临床妊娠率AH组高于非AH组，且差异均有
统计学意义。结论：激光辅助孵化技术的应用能够提升高龄患者的临床妊娠率，尤其是能显著提高冻融胚胎移植的种植率。

关键词: 激光辅助孵化, 高龄妇女, 冻融胚胎, 移植, 种植率, 临床妊娠率

Abstract:

Objective: To analyze the influence of laser-assisted hatching technology on the potential of elderly women's freezethawed
embryo transfer. Methods: 427 patients were grouped by age and assisted hatching（AH）. Comparison of embryos implantation
rate and clinical pregnancy rate were carried out among groups. Results: Among <35 years old patients, two groups' embryos
implantation rate of AH were higher than non-AH groups with statistically significant, but there was no difference in clinical pregnancy
rate and statistic; among ≥35 years old patients, embryo implantation rate and clinical pregnancy rate of AH group were higher than
non-AH group, and were statically significant. Conclusion: The application of laser-assisted hatching technology can increase clinical
pregnancy rate in elderly patients, especially in greatly promoting implantation rate of frozen-thawed embryo.
laser-assisted hatching|elderly women|frozen-thawed embryo|transplant; implantation rate|clinical pregnancy rate

Key words: laser-assisted hatching, elderly women, frozen-thawed embryo, transplant, implantation rate, clinical pregnancy rate

中图分类号:

R321.1

李正伟，许益娟，张若鹏. 激光辅助孵化对高龄妇女的冻融胚胎种植潜力的影响[J]. J4, 2016, 1(10): 57-60.

Li Zhengwei, Xu Yijuan, Zhang Ruopeng. Influence of Laser-assisted Hatching on the Potential of Elderly Women's
Frozen-thawed Embryo Implantation[J]. J4, 2016, 1(10): 57-60.

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