›› 2019, Vol. 4 ›› Issue (8): 73-75.

• 临床医学 • 上一篇    下一篇

大理州初筛Rh(D)阴性无偿献血者弱D(Rh(Du))分布情况

何永勋,王华,洪汾,叶文华,杜月娥,张林荔,梁艳娇   

  1. (大理州中心血站,云南大理671000)
  • 收稿日期:2018-03-02 修回日期:2019-03-10 出版日期:2019-08-15 发布日期:2019-08-15
  • 作者简介:何永勋,主任医师,主要从事血液免疫学研究.

The Weak D(Rh(D)u)Phenotype Distribution of Voluntary Blood Donors with Rh(D)-Negative Blood by
Screen Testing in Dali Prefecture

He Yongxun, Wang Hua, Hong Fen, Ye Wenhua, Du Yue'e, Zhang Linli, Liang Yanjiao   

  1. (Centre Blood Station of Dali Prefecture, Dali, Yunnan 671000, China)
  • Received:2018-03-02 Revised:2019-03-10 Online:2019-08-15 Published:2019-08-15

摘要:

目的:了解大理州初筛Rh(D)阴性无偿献血者中IgG抗-D血清检测结果为阳性的分布情况。方法:采用IgM+IgG抗-D
血清检测2009年1月至2014年7月无偿献血者样本153 862份,初步筛检出Rh(D)阴性献血者241例,再用3个不同批次的IgG
抗-D血清对阴性献血者Rh(D)及表现型作进一步检测。结果:11例血清学检测结果为弱D(Rh(Du)),各民族无偿献血者中
弱D的占比为汉族0.010%,白族0.004%,彝族0.005%,其他民族人数较少未检出。血清学表现型为CcDuee 、ccDuee 、CCDuee、
ccDuEe。该弱D献血者ABO血型分布情况B>O>A>AB。结论:大理州Rh(D)阴性无偿献血者有一定数量的弱D存在。

关键词: 献血者, Rh(D)阴性, 弱D

Abstract:

Objective: To understand the distribution of IgG anti-D-positive among voluntary blood donors with Rh(D)-negative
with screen testing in Dali Prefecture. Methods: IgM+IgG anti-D serum were used to test voluntary donors blood samples from January
2009 to July 2014. 241 Rh(D)-negative donors were preliminary screened as negative samples from 153 826 donors, and Rh(D)
phenotype were further tested with three different batches of IgG anti-D serum. Results: 11 samples were tested as weak D serological
phenotype(Rh(Du)). The proportions of weak D phenotype among the voluntary blood donors of all nationalities were 0.010% in the
Han nationality, 0.004% in the Bai nationality, and 0.005% in the Yi nationality. No weak D phenotype was detected in other
nationalities because of the small number of people. Serological phenotype included CcDuee, ccDuee, CCDuee, and ccDuEe. The
Distribution of ABO blood type of weak D phenotype donors was B>O>A>AB. Conclusion:Among the Rh(D)-negative voluntary
blood donors in Dali Prefecture, there are donors with weak D phenotype in varying degree.

Key words: blood donors, Rh(D)-negative, weak D phenotype

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