关键词: 肺炎感染, 细菌病原谱, 耐药性分布

Abstract:

Objective: To analyze the pathogenic spectrum and drug resistance distribution of pneumonia in inpatients, so as to
provide reference for the clinical treatment. Methods: The sputum of inpatients with pneumonia infection in the First People's Hospital
of Dali City from May 2016 to May 2017 was collected. Bacterial culture isolation, biochemical identification and drug susceptibility
test were carried out on sputum. The pathogenic spectrum and drug resistance distribution were statistically analyzed. Results: A total
of 287 strains of pathogenic bacteria were isolated, including 237 strains of Gram-negative bacteria, 43 strains of Gram-positive
bacteria and 7 strains of fungi. Results showed that Gram-negative bacteria were very sensitive to ertapenem, imipenem, meropenem,
amikacin（>98%）, were sensitive to gentamicin, ciprofloxacin, levofloxacin, piperacillin/tazobactam and cefepime（80% <sensitivity <
90%）, and were less sensitive to ampicillin, amoxicillin/clavulanic acid, piperacillin, etc（<60%）. Gram-positive bacteria had high
resistance to penicillin, erythromycin, clindamycin and tetracycline, and were sensitive to the rest. Conclusion: The pathogens isolated
from this investigation were mainly Gram- negative bacteria（82.58%）; all kinds of bacteria were multi-

Key words: pneumonia infection, bacterial pathogenic spectrum, distribution of drug resistance