›› 2019, Vol. 4 ›› Issue (8): 82-85.

• 临床医学 • 上一篇    下一篇

大理地区1 022例孕妇产前优生十项检测结果分析

马蓉1,徐弘扬1,杨锡彤2,李梦焕1,谢荣环1,王光明2*   

  1. (1.大理大学临床医学院,云南大理671000;2.大理大学第一附属医院基因检测中心,云南大理671000)
  • 收稿日期:2018-10-31 修回日期:2019-04-02 出版日期:2019-08-15 发布日期:2019-08-15
  • 通讯作者: 王光明,教授,博士,Email:gmwang1991@hotmail.com.
  • 作者简介:马蓉,硕士研究生,主要从事脑卒中、传染病研究.
  • 基金资助:

    云南省中青年学术技术带头人后备人才基金资助项目(2014HB025)

Prenatal TORCH Ten-Item Detection of 1 022 Pregnant Women in the Dali Area

Ma Rong1, Xu Hongyang1, Yang Xitong2, Li Menghuan1, Xie Ronghuan1, Wang Guangming2*   

  1. (1. Clinical Colloge, Dali University, Dali, Yunnan 671000, China; 2. Gene Detection Center, The First Affiliated Hospital of Dali
    University, Dali, Yunnan 671000, China)
  • Received:2018-10-31 Revised:2019-04-02 Online:2019-08-15 Published:2019-08-15

摘要:

目的:分析大理地区育龄妇女优生十项的检查结果及其临床意义。方法:以2015年1月至2017年12月到大理大学第
一附属医院做TORCH筛查的育龄女性为研究对象,收集病原标本1 022例,采用酶联免疫吸附法(ELISA)对血清TORCH特异
性抗体IgG及IgM进行检测。结果:1 022例病原标本中,共有1 012例检出抗体阳性,阳性率99.02%,其中HSVⅠIgG、HSVⅡ
IgG、CMV-IgG、RV-IgG、TOX-IgG 阳性率分别是77.10%、11.35%、95.89%、88.45%、14.29%。且联合感染的情况居多,以
HSVⅠ+CMV+RV-IgG阳性模式的人数最多,共520例(50.88%)。结论:TORCH血清学指标在大理地区人群中的分布情况主
要以IgG阳性居多,鉴于其阳性率较高,该地孕妇TORCH感染的情况有待改善,其次,由于无法判断病人的感染时机以及对新
生儿的影响,应该积极开展针对性的检查,做到早预防、早诊断,对母婴健康有一定的现实意义。

关键词: 孕妇, 优生十项, 大理地区

Abstract:

Objective: To analyze the results of prenatal TORCH examination in pregnant women and its clinical significance in Dali
area. Methods: The pregnant women who took TORCH screening in the First Affiliated Hospital of Dali University from January 2015 to
December 2017 were selected as the research subjects, and 1 022 cases of pathogenic specimens were collected. The serum specific
antibodies IgG and IgM of TORCH were detected by enzyme linked immunosorbent assay(ELISA). Results: Among these 1 022
pathogenic specimens, 1 012 were positive, with a positive rate of 99.02%. The positive rates of HSV Ⅰ IgG, HSV Ⅱ IgG, CMV-IgG,
RV-IgG and TOX-IgG were 77.10%, 11.35%, 95.89%, 88.45% and 14.29%. The incidence of co-infection was the most, and the
number of HSVⅠ+CMV+RV-IgG positive cases was the largest, with a total of 520 cases(50.88%). Conclusion: Firstly, the
distribution of serological indicators of TORCH in the local population is mainly IgG positive. The situation of TORCH infection needs to
be improved in this area because of its high positive rate. Secondly, due to the inability to judge the timing of infection and the impact on
the newborns, targeted examinations should be actively carried out, and early prevention and early diagnosis have certain practical
significance for maternal and infant health.

Key words: pregnant women, TORCH ten-item, Dali area

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