J4 ›› 2011, Vol. 10 ›› Issue (12): 16-20.

• 药学 • 上一篇    下一篇

微渗析-微分析联用技术在活体研究中的应用

微渗析取样是一种高效的生物活体取样技术,可与多种微纳分析设备组成联用对活体进行实时、在线分析。本文评述其技术原理、联用方式,应用范围及其局限性,并对其发展趋势进行预测,引用文献31 篇。   

  1. 大理学院药学与化学学院,云南大理 671000
  • 收稿日期:2011-04-12 修回日期:2011-09-06 出版日期:2011-12-15 发布日期:2011-12-15
  • 作者简介:杨志勇,讲师,博士,主要从事液相色谱、毛细管电泳技术在体内药物分析中的应用研究.
  • 基金资助:

    大理学院博士科研启动金项目(ky1019207610)

Application of Microdialysis-microanalysis Coupling Technique in Vivo Studies

Microdialysis sampling is an effective biological sampling technique in vivo, which has been coupled with many micronano analysis equipments for real-time,on-line analysis in vivo. In this review of 31 documents, the technical principle, combination mode, application range and limitation of microdialysis are stated and its development is predicted.   

  1. School of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China
  • Received:2011-04-12 Revised:2011-09-06 Online:2011-12-15 Published:2011-12-15

摘要:

微渗析取样是一种高效的生物活体取样技术,可与多种微纳分析设备组成联用对活体进行实时、在线分析。本文评述其技术原理、联用方式,应用范围及其局限性,并对其发展趋势进行预测,引用文献31 篇。

关键词: 微渗析, 活体取样, 在线联用, 评述

Abstract:

Microdialysis sampling is an effective biological sampling technique in vivo, which has been coupled with many micronano analysis equipments for real-time,on-line analysis in vivo. In this review of 31 documents, the technical principle, combination mode, application range and limitation of microdialysis are stated and its development is predicted.

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