RNA干扰的研究现状与应用前景

J4 ›› 2012, Vol. 11 ›› Issue (10): 52-55.

RNA干扰的研究现状与应用前景

RNA干扰（RNAi）是dsRNA介导的特异性基因表达沉默的现象，是生物在进化上高度保守的基因表达调节机制之一。从
RNA干扰的概念入手，系统阐述了RNA干扰的作用机制、作用特点及其最新进展，并对RNA干扰技术的应用前景进行了展望。

1.云南大学生命科学院生物化学与分子生物学实验室，昆明 650091；
2.大理学院基础医学院生物化学与分子生物学教研室，云南大理 671000

收稿日期:2011-09-26 修回日期:2011-11-24 出版日期:2012-10-15 发布日期:2012-10-15
作者简介:陈贵元，实验师，主要从事肿瘤细胞周期调控研究.
基金资助:
国家自然科学基金资助项目（30760057，30960091）

The Research Status and Application Prospect of RNA Interference

RNA interference (RNAi) is an evolutionarily conserved mechanism of gene regulation in almost all living organisms, with roles ranging from the developmental regulation of gene expression to defense mechanism against viral infections. In this paper, the concept, mechanism, basic characteristics and new research progress of RNA Interference are summarized. At the end, the application prospects of RNA Interference are described.

1. Laboratory of Biochemistry and Molecular Biology, 悦ollege of Life Science, Yunnan University, Kunming 650091,China;
2. Biochemistry and Moleculebiology Department, Pre-clinical College, Dali University, Dali, Yunnan 671000,China

Received:2011-09-26 Revised:2011-11-24 Online:2012-10-15 Published:2012-10-15

摘要/Abstract

摘要：

关键词: RNA干扰机制, 作用特点, 应用前景

Abstract:

Key words: RNAi mechanism, function characteristics, application prospect

中图分类号:

R979.1
R978

陈贵元, 谭德勇. RNA干扰的研究现状与应用前景[J]. J4, 2012, 11(10): 52-55.

CHEN Gui-Yuan, TAN De-Yong. The Research Status and Application Prospect of RNA Interference[J]. J4, 2012, 11(10): 52-55.

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