J4 ›› 2011, Vol. 10 ›› Issue (8): 1-4.
• 药学 • 下一篇
目的：探讨3 种方法求算药物溶出度Weibull分布参数的结果差别。方法：分别采用计算器、EXCEL和SPSS 软件处理药
物溶出数据。结果：3 种方法计算得到的T50、Td值和Weibull分布参数m 值很接近，但参数ζ和t0间相差较大。结论：药物溶出度Weibull 分布参数的计算结果在准确度上SPSS 法>EXCEL 法>计算器法。
Objective: To investigate different results through three methods of solving drug dissolution based on Weibull's
distribution parameter. Method: The data of drug dissolution based on Weibull's distribution were treated with statistic calculator, Microsoft Excel and SPSS software respectively. Result: T50, Td and m values were close in three methods, but ζ and t0 values were much different. Conclusion: Data from SPSS have shown highest accurate, EXCEL method was less accurate, statistic calculator was the most unreliable method.
摘要：
目的：探讨3 种方法求算药物溶出度Weibull分布参数的结果差别。方法：分别采用计算器、EXCEL和SPSS 软件处理药
物溶出数据。结果：3 种方法计算得到的T50、Td值和Weibull分布参数m 值很接近，但参数ζ和t0间相差较大。结论：药物溶出度Weibull 分布参数的计算结果在准确度上SPSS 法>EXCEL 法>计算器法。
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