含氟牙膏对脱矿恒牙釉质再矿化作用的体外研究

J4 ›› 2011, Vol. 10 ›› Issue (8): 7-9.

含氟牙膏对脱矿恒牙釉质再矿化作用的体外研究

大理学院药学与化学学院，云南大理 671000

收稿日期:2011-04-28 修回日期:2011-05-09 出版日期:2011-08-15 发布日期:2011-08-15
作者简介:陈俊霞，2009 级本科生.
基金资助:
大理学院药学与化学学院大学生科研基金资助项目（DXSKYY201012）

Re-mineralization Effect of Fluoride Toothpaste on Demineralized Enamel of Permanent Teeth in Vitro

School of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China

Received:2011-04-28 Revised:2011-05-09 Online:2011-08-15 Published:2011-08-15

摘要/Abstract

摘要：

目的：研究含氟牙膏对脱矿离体恒牙釉质的再矿化作用。方法：选取24 颗牙齿硬度在285 kg/mm²左右的脱矿离体牛恒
牙，随机分为A、B、C 3 组。A 组用含氟的纳爱斯营养维C 牙膏处理，B 组用不含氟的纳爱斯鲜浓果味牙膏处理，C 组不作任何处理，同时将3 组标本用人工唾液涂抹。然后用自动转塔数显显微维氏硬度计测定每颗牙齿硬度并记录。结果：A 组脱矿后恒牙硬度平均值285.2±4.3 与再矿化后牙齿硬度平均值356.9±7.9 比较，有统计学差异（P<0.05）；B 组脱矿恒牙的硬度平均值284±5.2与再矿化后牙齿硬度平均值302.3±3.8 比较无统计学差异（P>0.05）；C 组脱矿恒牙的硬度平均值285.3±5.1 与再矿化后牙齿硬度平均值272.0±6.6 比较无统计学差异（P>0.05）。再矿化后A 组牙齿硬度平均值显著高于B、C 两组（P<0.05）。结论：含氟牙膏能有效促进脱矿离体恒牙釉质的再矿化。

关键词: 含氟牙膏, 恒牙釉质, 再矿化, 硬度

Abstract:

Objective: To explore the effect of fluoride toothpaste on enamel re -mineralization of extracted permanent teeth.
Methods: Twenty-four enamel specimens of bovine intact permanent teeth were selected based on the hardness data of about 285 kg/mm² and were randomly divided into group A, B and C. Group A was treated with fluoride toothpaste, group B was treated with nonfluoride toothpaste, while group C was selected as the control group with non-treatment. All specimens were smeared with artificial saliva. The enamel microhardness of the three groups was measured by automatic turret digital micro Vickers hardness tester. Results: The mean hardness of group A before re-mineralization was（285.2±4.3）kg/mm ², while that after remineralization was （356.9±7.9）kg/mm²（P<0.05）; the mean hardness of group B before re-mineralization was（284±5.2）kg/mm2, while（302.3±3.8）kg/mm²（P>
0.05）after re-mineralization; the mean hardness of group C before re-mineralization was（285.3±5.1）kg/mm², and（272.0±6.6）kg/mm²（P>0.05）after re-mineralization. Data showed that the hardness value after re-mineralization of group A was apparently higher than those of group B and C （P<0.05）. Conclusion: Fluoride toothpaste can effectively promote the re-mineralization of demineralized enamel.

Key words: fluoride toothpaste, enamel of permanent teeth, re-mineralization, hardness

中图分类号:

R780. 2

陈俊霞, 李奇贤, 赵鹏, 崔春灵, 李雪珍, 蓝海. 含氟牙膏对脱矿恒牙釉质再矿化作用的体外研究[J]. J4, 2011, 10(8): 7-9.

CHEN Jun-Xia, LI Qi-Xian, ZHAO Peng, CUI Chun-Ling, LI Xue-Zhen, LAN Hai. Re-mineralization Effect of Fluoride Toothpaste on Demineralized Enamel of Permanent Teeth in Vitro[J]. J4, 2011, 10(8): 7-9.

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