J4 ›› 2014, Vol. 13 ›› Issue (8): 31-32.

• 临床医学 • 上一篇    下一篇

无创正压通气在早产儿呼吸窘迫综合征治疗中的价值分析

  

  1. 大理州妇幼保健院,云南大理 671000
  • 收稿日期:2014-01-28 出版日期:2014-08-15 发布日期:2014-08-15
  • 作者简介:李梅君,副主任医师,主要从事儿科临床研究.

Value Analysis of Noninvasive Positive Pressure Ventilation in the Treatment of Preterm Infants with
Respiratory Distress Syndrome

  1. Maternal and Child Health Care Hospital of Dali Prefecture, Dali, Yunnan 671000, China
  • Received:2014-01-28 Online:2014-08-15 Published:2014-08-15

摘要:

目的:分析鼻塞式持续正压通气(CPAP)在治疗早产儿呼吸窘迫综合征(NRDS)中的临床疗效,探讨持续呼吸道正压通
气在早产儿呼吸窘迫综合征治疗中的价值。方法:在综合治疗基础上,对大理州妇幼保健院新生儿科2012年10月至2013年10月84例胎龄为32~36周的早产RDS患儿给予CPAP治疗,观察患儿在应用CPAP前及CPAP治疗6 h后的疗效。结果:实施CPAP通气6 h后,患儿青紫消失,吸气性呼吸困难减轻,呼吸频率降至(58.2±4.7)次/min,心率降至(142.8±9.4)次/min,吸入氧浓度为(42.0±7.3)%,而经皮血氧饱和度维持在(94.8±4.5)%,动脉血氧分压升至(8.7±0.7)kPa,动脉血二氧化碳分压降至(5.3±0.6)kPa,差异具有统计学意义。应用CPAP期间除2例病情加重改用有创机械通气外未发生其他明显并发症。结论:使用CPAP对早产儿RDS有较好疗效,且治疗时间越早,痊愈率、成功率越高,无明显副作用。值得基层医院推广使用。

关键词: 鼻塞式持续正压通气, 新生儿呼吸窘迫综合征, 价值

Abstract:

Objective: To analyze clinical efficacy of nasal continuous positive airway pressure ventilation(CPAP)in the treatment
of preterm infants with respiratory distress syndrome(NRDS)and explore the value of CPAP for NRDS preterm infants. Methods:Based on combined therapy, CPAP was adopted for 84 cases with RDS from Oct. 2012 to Oct. 2013 at the neonatal department of the Maternal and Child Health Care Hospital of Dali Prefecture with the neonatal gestation age between 32 and 36 weeks. The efficacy was observed before the adoption of CPAP and six hours after the adoption of CPAP. Results: Six hours after the adoption of CPAP, cyanosis disappeared, inspiratory dyspnea was alleviated, the respiratory rate dropped to(58.2±4.7)/min, the heart rate dropped to (142.8±9.4)/min, fraction of inspired oxygen was(42.0±7.3)%, percutaneous oxygen saturation remained(94.8±4.5)%, the arterial
partial pressure of oxygen fell to(8.7±0.7)kPa and arterial partial pressure of carbon dioxide fell to(5.3±0.6)kPa, which showed significant difference. There was no other obvious complication except that the condition of 2 cases aggravated and therefore invasive mechanical ventilation was adopted. Conclusion: CPAP had a good curative effect on RDS preterm infants and the side effect was not serious and the earlier the treatment begun, the higher the cure rate and success rate were. Therefore, CPAP was worthy of introduction and promotion in primary hospitals.

Key words: nasal continuous positive airway pressure ventilation(CPAP), Neonatal Respiratory Distress Syndrome(NRDS), value

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