滇西高海拔地区健康人群慢性高原病风险分析

J4 ›› 2015, Vol. 14 ›› Issue (8): 35-40.

滇西高海拔地区健康人群慢性高原病风险分析

（中国人民解放军第60中心医院，云南大理671003）

收稿日期:2015-03-25 出版日期:2015-08-15 发布日期:2015-08-15
作者简介:资云海，副主任医师，主要从事预防医学研究.

Risk Analysis of the Chronic Mountain Sickness（CMS）in Healthy Population living in the Western Yunnan Plateau

（60 Central Hospital of PLA, Dali, Yunnan 671003, China）

Received:2015-03-25 Online:2015-08-15 Published:2015-08-15

摘要/Abstract

摘要：

目的：探讨云南滇西高海拔地区健康人群慢性高原病（CMS）的发病风险。方法：从骨密度、血细胞分析、血液流变学、
血液生化和免疫功能等5个方面对不同海拔高度地区健康人群慢性高原病的发病风险进行分析。结果：随着海拔升高，人群
骨密度逐渐增加；血液RBC、Hb等逐渐增高，血液黏稠度增加，差异有统计学意义（P＜0.05）；肝功能除TP、Alb及Glu外其余指
标均随海拔升高而升高，肾功能和心肌酶谱各指标亦随海拔升高而升高；大理组和维西组TC、TG、LDL-C、APoB、IgG、IgM、
IgA、C3、C4水平显著低于香格里拉组（P＜0.05），低于德钦组（P＜0.05）；随海拔升高，CD3+、CD8+逐渐增高且相邻两组间差异
有统计学意义（P＜0.05）。结论：健康人群各项功能指标随海拔升高有不同的改变，患慢性高原病的危险性逐渐增加。

关键词: 滇西, 高海拔地区, 慢性高原病, 发病风险

Abstract:

Objective: To investigate the CMS risk of healthy population in western Yunnan plateau. Methods: CMS risk of healthy
population living at different districts was analyzed in 5 ways: bone density measurement, blood routine examination, hemorheological
analysis, blood biochemistry and immunologic function. Results: The bone density of people gradually increased with elevation. RBC
and Hb gradually increased and blood viscosity increased, the difference was statistically significant（P＜0.05）. Except for TP, Alb
and Glu, other indexes of liver function increased with elevation. Indexes of renal function and myocardial enzymes increased as
altitude rose（P＜0.05）. The TC, TG, LDL-C, APoB level of Dali and Weixi group were significantly lower than those of Shangri-La
group（P＜0.05）, and these were even lower than Deqin group（P＜0.05）. The IgG, IgM, IgA, C3, C4 and CD3+, CD8+ level of Dali
and Weixi group were significantly lower than Shangri- La group（P＜0.05）, and were still lower than Deqin group（P＜0.05）.
Conclusion: The indexes of bone density measurement, blood routine examination, hemorheological analysis, blood biochemistry and
immunologic function of healthy people varied differently, and the CMS risk gradually increased.

Key words: western Yunnan, plateau, CMS, risk

中图分类号:

R594.3

资云海，子建文，李倩，张玉岭，唐辉，龚念婷. 滇西高海拔地区健康人群慢性高原病风险分析[J]. J4, 2015, 14(8): 35-40.

Zi Yunhai, Zi Jianwen, Li Qian, Zhang Yuling, Tang Hui, Gong Nianting. Risk Analysis of the Chronic Mountain Sickness（CMS）in Healthy Population living in the Western Yunnan Plateau[J]. J4, 2015, 14(8): 35-40.

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