A Feature Gene Selection Method Based on Traversal Gene Combination

Abstract

Abstract:

Feature gene selection is a hot issue. Under the consumption that cancer is caused by one or some genes heteromorphosis,
this article starts research from two genes combination, using Logistic regression method on all possible combinations with 2 genes with
prediction accuracy and AIC as the evaluation criteria. Based on the evaluation of all stimulation results, we obtained the best gene
combination（X55187, D14812）. Meanwhile, we tested and verified the stability of this best combination（X55187, D14812）with
leave one out cross validation. At last, we analyzed and compared the frequencies of 640 pairs gene combination which prediction
accuracy was more than 90% with former studies. The result shows that prediction accuracy is not high along with the higher frequency
gene combination.

Key words: colon cancer, feature genes, Logistic regression, traversal

CLC Number:

O212.6

LI Jie. A Feature Gene Selection Method Based on Traversal Gene Combination[J]. J4, 2015, 14(6): 1-4.

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