Influence of Tranexamic Acid on Hidden Blood Loss after the Total Knee Arthroplasty

Abstract

Abstract:

Objective: To discuss the influence of tranexamic acid on hidden blood loss after the total knee arthroplasty（TKA）.
Methods: The changes of hemoglobin（Hb）of 211 patients who had undergone TKA in Panzhihua Central Hospital from January 2014
to December 2016 were analyzed before and 1 day, 3 days and 1 week after the surgeries. From January 2014 to June 2015, 100
patients did not receive tranexamic acid during the surgeries, and from July 2015 to December 2016, 111 patients received tranexamic
acid during the surgeries as required. Their hemoglobin were analyzed and the influence of tranexamic acid on hidden blood loss was
deduced. Results: In the third day and one week after the surgeries, the indexes of hemoglobin was statistically different（P<0.05）
between the patients who had used tranexamic acid and those who had not, whereas there was no significant difference（P>0.05）in the
first day after the surgeries. Conclusion: The application of tranexamic acid can significantly reduce the hidden blood loss after TKA.
So it can be used in part of the patients, but the coagulation function should be closed assessed at the same time.

Key words: tranexamic acid, total knee arthroplasty（TKA）, hidden blood loss, hemoglobin

CLC Number:

R687.4

WANG Hong-Beng, LAN Yu-Beng, DAO Qi-Feng, TUN Fei-Feng, CHEN Chun-Yu. Influence of Tranexamic Acid on Hidden Blood Loss after the Total Knee Arthroplasty[J]. , 2019, 4(8): 46-49.

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