Journal of Dali University ›› 2022, Vol. 7 ›› Issue (10): 15-21.

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Evaluation of the Drug Utilization of Young Patients with Cerebral Ischemic Stroke in a Hospital in Dali City by DUR and DUE

Wu RongshuangMa AncuiShen Lei* #br#   

  1. 1.College of PharmacyDali UniversityDaliYunnan 671000China2. Department of PharmacyThe First Affiliated Hospital of Dali UniversityDaliYunnan 671000China

  • Received:2022-04-22 Revised:2022-08-11 Online:2022-10-15 Published:2022-11-15

Abstract:

AbstractObjectiveTo evaluate the drug utilization and rationality of young patients with cerebral ischemic stroke in the First Affiliated Hospital of Dali University from 2018 to 2020. MethodsDrug utilization reviewDURand drug utilization evaluationDUEwere used to evaluate the typefrequency and rationality of drugs used by patients. Results61 drugs in 13 categories were applied in the treatment of 75 patientsincluding 48 western drugs and 13 traditional Chinese medicine injectionsamong which the proportion of lipid-regulating drugs was the highestreaching 98.7%. DUR results showed that the drug utilization indexDUIof 11 drugs was greater than 1the DUI of 24 drugs was 1and the DUI of 26 drugs was less than 1. Western drugs with DUI greater than 1 were mainly acid inhibitor and antihypertensive drugswhile drugs with DUI less than 1 were of a wide varietymostly caused by dose reduction in combination drugs. DUE results showed that the monitoring rate of drug-related laboratory test indicators was lowand the main adverse reactions were gastrointestinal reactions. After drug treatmentthe clinical symptoms of 74 patients were improved. ConclusionThe selection of drugs for young patients with cerebral ischemic stroke in this hospital is reasonablebut it is necessary to strengthen the management of acid inhibitor and antihypertensive drugsand strengthen the monitoring of related laboratory indicators and adverse reactions during treatment.

Key words:

"> font-size:10.5pt, ">cerebral ischemic stroke, youth, drug utilization review, drug utilization evaluation, adverse reactions

CLC Number: