Ａnalysis of S100P Gene Expression and Clinical Significance in Breast Cancer Based on Bioinformatics

Abstract

Abstract:

〔Abstract〕 Objective： To investigate the expression and clinical significance of S100P gene in breast cancer. Methods：A variety of online bioinformatics databases were used to analyze the molecular expression， regulatory network and prognostic value of S100P. Results：The expression level of S100P gene in breast cancer was significantly higher than that in normal tissues （P<0.05）. S100P expression was correlated with lymph node metastasis in breast cancer （P<0.05）， and high expression level was associated with poor prognosis （P<0.001）. S100P was mainly involved in biological processes such as glycosylation and granulocyte activation， and was related to proteasome， IL-17 and other signal pathways. Conclusion：High expression of S100P in breast cancer is a potential target for diagnosis， treatment and prognosis of breast cancer.

Key words:

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CLC Number:

Xu Kang, Bai Li.

Ａnalysis of S100P Gene Expression and Clinical Significance in Breast Cancer Based on Bioinformatics [J]. Journal of Dali University, 2022, 7(10): 68-74.

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