Comparative Study on Six Kinds of Medicinal Plants in Tibetan Medicine "Dida" on Preventing Chronic
Hepatic Injury

Abstract

Abstract:

Objective: To compare the protective effect of six kinds of medicinal plants in Tibetan medicine "Dida" on chemical
hepatic injury. Methods: Carbon tetrachloride（CCl4）was used to cause chemical hepatic injury in mice to form the model group. The
serum hepatic injury index was used to detected the hepatoprotective effect of six medicinal plants of liver injury induced by serum
indicators to compare the effect of 6 species of medicinal plants. Results: Compared with the model group, six medicinal plants can
significantly reduce serum alanine transaminase（ALT）and aspartate aminotransferase（AST）activity, and increase total protein
（TP）and total bilirubin reduction（TBI）content. Compared with equivalent dose Swertia mileensis, Swertia chirayita（Roxb.ex Flemi）
Karsten, Swertia mussotii, Swertia punicea, Halenia elliptica, Saxifraga tangutica reduced ALT, AST, TBI and increased TP without
significant difference. Conclusion: Hepatoprotective effect on chemical hepatic injury of Swertia mileensis and other five kinds of
medicinal plants in "Dida" had no significant difference.

Key words: Tibetan medicine "Dida", Swertia mileensis, CCl4, hepatoprotective effect

CLC Number:

R285

Guo Yongqiang, Shen Lei, Yang Xiaoquan, Xia Conglong. Comparative Study on Six Kinds of Medicinal Plants in Tibetan Medicine "Dida" on Preventing Chronic
Hepatic Injury[J]. , 2017, 2(4): 16-19.

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