Research in miRNA-mRNA Regulatory Network Based on NetMatchStar
（1.College of Engineering, Dali University, Dali, Yunnan 671003, China; 2. College of Agriculture and Biology Science,
Dali University, Dali, Yunnan 671003, China）
〔1〕BARTEL D P. MicroRNAs：genomics，biogenesis，mecha?
nism，and function〔J〕. Cell，2004，116（2）：281-297.
〔2〕LIN S，GREGORY R I. MicroRNA biogenesis pathways in
cancer〔J〕. Nature Reviews Cancer，2015，15（6）：321-333.
〔3〕MILO R，SHEN-ORR S S，ITZKOVITZ S，et al. Network
motifs：simple building blocks of complex networks〔J〕. Sci?
ence，2002，298（5594）：824-827.
〔4〕CHOU C H，CHANG N W，SHRESTHA S，et al. miRTar?
Base 2016：updates to the experimentally validated miR?
NA- target interactions database〔J〕. Nucleic Acids Re?
search，2015，44（D1）：D239-D247.
〔5〕VLACHOS I S，PARASKEVOPOULOU M D，KARAGK?
OUNI D，et al. DIANA-TarBase v7. 0：indexing more than
half a million experimentally supported miRNA：mRNA
interactions〔J〕. Nucleic Acids Research，2014，43（D1）：
D153-D159.
〔6〕DWEEP H，GRETZ N. miRWalk2. 0：a comprehensive at?
las of microRNA-target interactions〔J〕. Nature Methods，
2015，12（8）：697.
〔7〕LEX A，GEHLENBORG N，STROBELT H，et al. UpSet：vi?
sualization of intersecting sets〔J〕. IEEE Transactions on
Visualization and Computer Graphics，2014，20（12）：
1983-1992.
〔8〕RINNONE F，MICALE G，BONNICI V，et al. NetMatch?
Star：an enhanced Cytoscape network querying app〔J〕.
F1000Research，2015，4：479.
〔9〕SHANNON P，MARKIEL A，OZIER O，et al. Cytoscape：a
software environment for integrated models of biomolecular
interaction networks〔J〕. Genome Research，2003，13（11）：
2498-2504.
〔10〕RAHMATI S，ABOVSKY M，PASTRELLO C，et al. path?
DIP：an annotated resource for known and predicted human
gene-pathway associations and pathway enrichment analy?
sis〔J〕.NucleicAcidsResearch，2017，45（D1）：D419-D426.
