Journal of Dali University ›› 2020, Vol. 5 ›› Issue (2): 88-92.DOI: 10. 3969 / j. issn. 2096-2266. 2020. 02. 020

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Correlation between Serum α-L-Fucosidase and Blood Lipids in Late Pregnant Women

Zhu Jiangxian 1 , Shen Huaxian 2 , Yao Xiyou 1*   

  1. （1. Department of Clinical Laboratory, People′s Hospital of Yuxi City, Yuxi, Yunnan 653100, China; 2. Center Blood Station of
    Yuxi City, Yuxi, Yunnan 653100, China）
  • Received:2019-01-02 Revised:2019-04-02 Online:2020-02-15 Published:2020-02-15

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Abstract: Objective: To investigate the changes of serum α-L-fucosidase（AFU）and blood lipids in pregnant women and the
correlation between the two factors to provide guidance for the diagnosis of hyperlipidaemia in late pregnant women. Methods: The
subjects were divided into three groups: the early and middle pregnancy group before 28th week of gestation, the late pregnancy group
after 28th week of gestation and the healthy non-pregnancy group. Serum AFU and blood lipid concentration were detected in each
group and analyzed by SPSS software. Results: Compared with non-pregnancy group, AFU in late pregnancy group was significantly
higher（P<0.05）. Triglyceride（TG）, total cholesterol（TC）, low density lipoprotein（LDL）, very low density lipoprotein（VLDL）,
apolipoprotein A（ApoA）and apolipoprotein B（ApoB）were significantly higher（P<0.05）. In the late pregnancy group, with the
increase of gestational weeks, AFU and blood lipids such as TG, TC, LDL, VLDL, ApoA and ApoB increased gradually, and there was a
correlation between them（P<0.05, r＞0.9）. Conclusion: The serum AFU and blood lipid levels of late pregnant women could change,
and there are correlation between serum AFU and blood lipids. Serum AFU can help evaluate the blood lipid level of late pregnant
women.

Key words: pregnancy, α-L-fucosidase, blood lipid, correlation