Journal of Dali University ›› 2024, Vol. 9 ›› Issue (8): 10-13.DOI: 10. 3969 / j. issn. 2096-2266. 2024. 08. 002

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Study on Aromadendrane and Guaiane Sesquiterpenoids from the Rhizome of Dobinea delavayi

Zhao Xuan1, 2, 3, Dong Litian1, 2, 3, Chen Wei1, 2, 3, Shen Yi1, 2, 3, Li Gang1, 2, 3, Xiao Chaojiang1, 2, 3, Jiang Bei1, 2, 3*   

  1. （1. Yunnan Key Laboratory of Screening and Research on Anti-pathogenic Plant Resources from Western Yunnan,
    Dali, Yunnan 671000, China; 2. College of Pharmacy, Dali University, Dali, Yunnan 671000, China;
    3. Institute of Materia Medica, Dali University, Dali, Yunnan 671000, China）
  • Received:2024-01-15 Revised:2024-01-24 Online:2024-08-15 Published:2024-08-12

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Abstract: Objective: To gain a deeper understanding of the types and structures of sesquiterpenoids in the extract of Dobinea
delavayi, and to provide scientific basis for the development and utilization of this plant. Methods: Silica gel and Sephadex LH-20
column chromatography were used to separate and purify sesquiterpenoids from 80% ethanol extract of dried rhizome of D. delavayi,
and the compounds were structurally characterized on the basis of physicochemical properties and modern spectroscopic techniques.
Results: Six sesquiterpenoid compounds were isolated and identified as: 4β, 10β, 15-trihydroxy-aromadendrane-10, 15-acetonide
（1）, 4α-hydroxy-10β-methoxy-1β-H, 5β-H-aromadendrane （2）, 4β, 10β⁃aromadendranediol （3）, spathulenol （4）, 2-oxoguaia-1
（10）, 3, 5, 7（11）, 8-pentaen-12, 8-olide （5）, and taraxacin （6）. Conclusion: D. delavayi contains aromadendrane sesquiterpenoids
and guaiane sesquiterpenoids. This study provides a research basis for a deeper understanding of the chemical quality of D. delavayi.

Key words: Dobinea delavayi, rhizome, chemical quality, aromadendrane sesquiterpenoids, guaiane sesquiterpenoids

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