J4 ›› 2012, Vol. 11 ›› Issue (9): 25-28.

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In vitro Study of the Effect of Scallop Shells Extract on Fat Degradation

Objective: To investigate the effect of scallop shells on fat degradation and find new ways to increase their added value.
Methods: To evaluate the effect of bioactive substances of scallop shells on fat degradation, 3T3-L1 cells were treated with methanol extract of scallop shells, the amounts of glycerol secreted from 3T3-L1 cells were measured and the fat contents in 3T3-L1 cells were observed by Oil Red O staining. Results: 3T3-L1 cells treated with scallop shell extract secreted more glycerol (P<0.05) and were with less fat. Conclusion: This study provided evidence that bioactive substances in scallop shells promote fat degradation, which suggests a potential value of scallop shells.   

  1. 1. Collgeg of Pharmacy and Chemistry, Dali University, Dali, Yunnan 671000, China;
    2. Pre-clinical College, Dali University, Dali, Yunnan 671000, China
  • Received:2012-07-20 Revised:2012-08-26 Online:2012-09-15 Published:2012-09-15

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Abstract:

Objective: To investigate the effect of scallop shells on fat degradation and find new ways to increase their added value.
Methods: To evaluate the effect of bioactive substances of scallop shells on fat degradation, 3T3-L1 cells were treated with methanol extract of scallop shells, the amounts of glycerol secreted from 3T3-L1 cells were measured and the fat contents in 3T3-L1 cells were observed by Oil Red O staining. Results: 3T3-L1 cells treated with scallop shell extract secreted more glycerol (P<0.05) and were with less fat. Conclusion: This study provided evidence that bioactive substances in scallop shells promote fat degradation, which suggests a potential value of scallop shells.

Key words: scallop shells, 3T3-L1 fat cells, lipolysis

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