Abstract:

Objective: To observe the clinical efficacy and safety of bacterial meningitis treated by latamoxef sodium. Methods:
Retrospective investigation to the bacterial mengitis cases in our hospital in the past 5 years was taken. Forty cases were randomly selected and divided into the latamoxef sodium 50 mg/kg treatment group（group A）and the cefepime 50 mg/kg control group（group B）, each with 20 cases. Then the clinical efficacy, bacteriological changes and adverse reactions were compared between the two groups. Results: The clinical efficacy of group A and B was 95.00% and 90.00% respectively, without significant difference （P>0.05）. Conclusion: Latamoxef sodium treating bacterial meningitis, which had higher efficacy, safety and less adverse reaction, could reach a win-win situation for both the medical institutions and the patients under the system of new rural cooperative medicare scheme and urban health insurance. It is wealthy of clinical application.

Key words: latamoxef sodium, cefepime, bacterial menigitis