Abstract:

Objective: To evaluate the clinical effects of lidocaine combined with iodine glycerol on recurrent aphthous ulcer
（RAU）.Methods: Eighty-three cases of RAU were randomly divided into two groups, the treatment group （n=43）were treated with lidocine combined with iodine glycerol, and the control group（n=40）were applied gargle compound chlorhexidine. Healing effects of ulcers in 3 days, 5 days and 7 days after treatment were observed and compared. Results: The effective rate was 97.7% in treatment group and 57.5% in control group. There was significant difference in effective rate between the two groups （P<0.05）. Conclusion: Lidocaine combined with iodine glycerol was a good method in treating recurrent aphthous ulcer.

Key words: reccurrent aphthous ulcer, lidocaine, iodine glycerol, combined therapy