Abstract:

Objective: To investigate the effect of Ganlong capsule and Periplaneta americana skimmed cream on bile secretion of
normal rats. Methods: 80 rats were randomly divided into groups. After seven consecutive days of intragastric administration of 20
mL/kg once a day to each group, the effect was observed by the bile flow experiment and the analysis of bile composition. Results:
Ganlong capsule had no choleretic effec, and no effect on bile compositon. Periplaneta americana skimmed cream had choleretic effect,and compared with NS group, the difference in the bile flow was statistically significant (P < 0.05), and the content of TBL, DBL and IBL in bile decreased (P < 0.05). Conclusion: Ganlong capsule had no choleretic effect; Periplaneta americana skimmed cream had choleretic effect.

Key words: Ganlong capsule, Periplaneta americana skimmed cream, choleretic effect